FBL14_ARATH
ID FBL14_ARATH Reviewed; 480 AA.
AC Q3EC97; Q9M8M4;
DT 23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2005, sequence version 1.
DT 25-MAY-2022, entry version 107.
DE RecName: Full=F-box/LRR-repeat protein 14;
GN Name=FBL14; OrderedLocusNames=At1g80570; ORFNames=T21F11.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11077244; DOI=10.1016/s1360-1385(00)01769-6;
RA Xiao W., Jang J.-C.;
RT "F-box proteins in Arabidopsis.";
RL Trends Plant Sci. 5:454-457(2000).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q3EC97-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q3EC97-2; Sequence=VSP_022377;
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DR EMBL; AC018849; AAF27118.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE36421.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE36422.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE36423.1; -; Genomic_DNA.
DR EMBL; BT002966; AAO22775.1; -; mRNA.
DR EMBL; BT004407; AAO42401.1; -; mRNA.
DR PIR; G96837; G96837.
DR RefSeq; NP_565240.1; NM_106705.3. [Q3EC97-2]
DR RefSeq; NP_974191.1; NM_202462.1. [Q3EC97-1]
DR RefSeq; NP_974192.1; NM_202463.1. [Q3EC97-2]
DR AlphaFoldDB; Q3EC97; -.
DR SMR; Q3EC97; -.
DR STRING; 3702.AT1G80570.2; -.
DR PaxDb; Q3EC97; -.
DR PRIDE; Q3EC97; -.
DR ProteomicsDB; 222497; -. [Q3EC97-1]
DR EnsemblPlants; AT1G80570.1; AT1G80570.1; AT1G80570. [Q3EC97-2]
DR EnsemblPlants; AT1G80570.2; AT1G80570.2; AT1G80570. [Q3EC97-1]
DR EnsemblPlants; AT1G80570.3; AT1G80570.3; AT1G80570. [Q3EC97-2]
DR GeneID; 844396; -.
DR Gramene; AT1G80570.1; AT1G80570.1; AT1G80570. [Q3EC97-2]
DR Gramene; AT1G80570.2; AT1G80570.2; AT1G80570. [Q3EC97-1]
DR Gramene; AT1G80570.3; AT1G80570.3; AT1G80570. [Q3EC97-2]
DR KEGG; ath:AT1G80570; -.
DR Araport; AT1G80570; -.
DR TAIR; locus:2198883; AT1G80570.
DR eggNOG; KOG1947; Eukaryota.
DR InParanoid; Q3EC97; -.
DR OMA; PSYNANC; -.
DR OrthoDB; 1046098at2759; -.
DR PhylomeDB; Q3EC97; -.
DR PRO; PR:Q3EC97; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q3EC97; baseline and differential.
DR Genevisible; Q3EC97; AT.
DR GO; GO:0019005; C:SCF ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR Gene3D; 3.80.10.10; -; 3.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR Pfam; PF13516; LRR_6; 2.
DR SMART; SM00367; LRR_CC; 6.
DR PROSITE; PS50181; FBOX; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Leucine-rich repeat; Reference proteome; Repeat.
FT CHAIN 1..480
FT /note="F-box/LRR-repeat protein 14"
FT /id="PRO_0000272254"
FT DOMAIN 11..58
FT /note="F-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT REPEAT 61..86
FT /note="LRR 1"
FT REPEAT 94..119
FT /note="LRR 2"
FT REPEAT 120..144
FT /note="LRR 3"
FT REPEAT 145..170
FT /note="LRR 4"
FT REPEAT 171..196
FT /note="LRR 5"
FT REPEAT 197..222
FT /note="LRR 6"
FT REPEAT 229..257
FT /note="LRR 7"
FT REPEAT 258..283
FT /note="LRR 8"
FT REPEAT 284..309
FT /note="LRR 9"
FT REPEAT 322..347
FT /note="LRR 10"
FT REPEAT 355..379
FT /note="LRR 11"
FT REPEAT 380..404
FT /note="LRR 12"
FT REPEAT 405..429
FT /note="LRR 13"
FT REPEAT 430..454
FT /note="LRR 14"
FT REPEAT 455..480
FT /note="LRR 15"
FT VAR_SEQ 1..13
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:14593172"
FT /id="VSP_022377"
SQ SEQUENCE 480 AA; 53598 MW; BD512F99355CD53C CRC64;
MFIGIAYLGG DRQMDELPDH LVWDILSKLH TTDDRNSLSL SCKRFFSLDN EQRYSLRIGC
GLVPASDALL SLCRRFPNLS KVEIIYSGWM SKLGKQVDDQ GLLVLTTNCH SLTDLTLSFC
TFITDVGIGH LSSCPELSSL KLNFAPRITG CGVLSLAVGC KKLRRLHLIR CLNVASVEWL
EYFGKLETLE ELCIKNCRAI GEGDLIKLRN SWRKLTSLQF EVDANYRYMK VYDQLDVERW
PKQLVPCDSL VELSLGNCII APGRGLACVL RNCKNLEKLH LDMCTGVSDS DIIALVQKAS
HLRSISLRVP SDFTLPLLNN ITLRLTDESL SAIAQHCSKL ESFKISFSDG EFPSLFSFTL
QGIITLIQKC PVRELSLDHV CVFNDMGMEA LCSAQKLEIL ELVHCQEVSD EGLILVSQFP
SLNVLKLSKC LGVTDDGMRP LVGSHKLELL VVEDCPQVSR RGVHGAATSV SFKQDLSWMY