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FBL35_ARATH
ID   FBL35_ARATH             Reviewed;         352 AA.
AC   Q1PEY8; Q8GUS8; Q8GUS9; Q9SIK6;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=F-box/LRR-repeat protein At2g29910;
GN   OrderedLocusNames=At2g29910; ORFNames=F6K5.4;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC   STRAIN=cv. Columbia;
RX   PubMed=16244158; DOI=10.1104/pp.105.063479;
RA   Xiao Y.-L., Smith S.R., Ishmael N., Redman J.C., Kumar N., Monaghan E.L.,
RA   Ayele M., Haas B.J., Wu H.C., Town C.D.;
RT   "Analysis of the cDNAs of hypothetical genes on Arabidopsis chromosome 2
RT   reveals numerous transcript variants.";
RL   Plant Physiol. 139:1323-1337(2005).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC   STRAIN=cv. Columbia;
RX   PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA   Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT   "Simultaneous high-throughput recombinational cloning of open reading
RT   frames in closed and open configurations.";
RL   Plant Biotechnol. J. 4:317-324(2006).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q1PEY8-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q1PEY8-2; Sequence=VSP_024103;
CC   -!- MISCELLANEOUS: [Isoform 2]: May be due to intron retention.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAD23631.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC007113; AAD23631.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002685; AEC08319.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC08320.1; -; Genomic_DNA.
DR   EMBL; CP002685; ANM61629.1; -; Genomic_DNA.
DR   EMBL; CP002685; ANM61630.1; -; Genomic_DNA.
DR   EMBL; CP002685; ANM61632.1; -; Genomic_DNA.
DR   EMBL; CP002685; ANM61633.1; -; Genomic_DNA.
DR   EMBL; AY169001; AAO11672.1; -; mRNA.
DR   EMBL; AY169002; AAO11673.1; -; mRNA.
DR   EMBL; DQ446579; ABE65873.1; -; mRNA.
DR   PIR; B84702; B84702.
DR   RefSeq; NP_001323834.1; NM_001336230.1. [Q1PEY8-1]
DR   RefSeq; NP_001323835.1; NM_001336231.1. [Q1PEY8-1]
DR   RefSeq; NP_001323837.1; NM_001336233.1. [Q1PEY8-1]
DR   RefSeq; NP_001323838.1; NM_001336229.1. [Q1PEY8-2]
DR   RefSeq; NP_180552.2; NM_128545.6. [Q1PEY8-1]
DR   RefSeq; NP_850138.1; NM_179807.3. [Q1PEY8-2]
DR   AlphaFoldDB; Q1PEY8; -.
DR   BioGRID; 2891; 2.
DR   IntAct; Q1PEY8; 1.
DR   PaxDb; Q1PEY8; -.
DR   PRIDE; Q1PEY8; -.
DR   EnsemblPlants; AT2G29910.1; AT2G29910.1; AT2G29910. [Q1PEY8-1]
DR   EnsemblPlants; AT2G29910.2; AT2G29910.2; AT2G29910. [Q1PEY8-2]
DR   EnsemblPlants; AT2G29910.3; AT2G29910.3; AT2G29910. [Q1PEY8-2]
DR   EnsemblPlants; AT2G29910.4; AT2G29910.4; AT2G29910. [Q1PEY8-1]
DR   EnsemblPlants; AT2G29910.5; AT2G29910.5; AT2G29910. [Q1PEY8-1]
DR   EnsemblPlants; AT2G29910.7; AT2G29910.7; AT2G29910. [Q1PEY8-1]
DR   GeneID; 817541; -.
DR   Gramene; AT2G29910.1; AT2G29910.1; AT2G29910. [Q1PEY8-1]
DR   Gramene; AT2G29910.2; AT2G29910.2; AT2G29910. [Q1PEY8-2]
DR   Gramene; AT2G29910.3; AT2G29910.3; AT2G29910. [Q1PEY8-2]
DR   Gramene; AT2G29910.4; AT2G29910.4; AT2G29910. [Q1PEY8-1]
DR   Gramene; AT2G29910.5; AT2G29910.5; AT2G29910. [Q1PEY8-1]
DR   Gramene; AT2G29910.7; AT2G29910.7; AT2G29910. [Q1PEY8-1]
DR   KEGG; ath:AT2G29910; -.
DR   Araport; AT2G29910; -.
DR   TAIR; locus:2052085; AT2G29910.
DR   HOGENOM; CLU_010721_7_2_1; -.
DR   InParanoid; Q1PEY8; -.
DR   OMA; KRICAHR; -.
DR   PhylomeDB; Q1PEY8; -.
DR   PRO; PR:Q1PEY8; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q1PEY8; baseline and differential.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR013101; Leu-rich_rpt_2.
DR   Pfam; PF00646; F-box; 1.
DR   Pfam; PF07723; LRR_2; 1.
DR   SUPFAM; SSF81383; SSF81383; 1.
DR   PROSITE; PS50181; FBOX; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Leucine-rich repeat; Reference proteome; Repeat.
FT   CHAIN           1..352
FT                   /note="F-box/LRR-repeat protein At2g29910"
FT                   /id="PRO_0000281936"
FT   DOMAIN          4..50
FT                   /note="F-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT   REPEAT          101..124
FT                   /note="LRR 1"
FT   REPEAT          149..173
FT                   /note="LRR 2"
FT   REPEAT          175..199
FT                   /note="LRR 3"
FT   REPEAT          298..323
FT                   /note="LRR 4"
FT   VAR_SEQ         314..352
FT                   /note="FYFCCKSMPVFHNLLTLSFESAKKEAGQCCHFSSISLLT -> SFPYLLLFQ
FT                   FEVHSSLQSLLIV (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:16244158"
FT                   /id="VSP_024103"
FT   CONFLICT        62
FT                   /note="F -> L (in Ref. 3; AAO11672/AAO11673)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   352 AA;  39502 MW;  7527B6D088659ED5 CRC64;
     MGSRDLISSL PDEILGKVLS LLPTKRAAST AVLSKRWNNL PALVDKLDIN DAIGGPGGFP
     EFIDKTLALL TNSTTIKRTS LNNEFQYGES QVNTWIRSFL ERGCLQLYLN AQSLYTIDTE
     FFTSNTLVEL TITGGFSPDG LLPPGGVFFP KLKTLSLVLM TFVDSDMYEL FISGCPLLEE
     FLLRNDEIEI PPVWNALVSS PSIKRLTIVH HFPNYREAHD GCWFRTPNLV YLDYSSYVPD
     WYEVDLGSLV EARLDLRSWE RLRDEKAGGY GDCDSVYDDE EYPDDPILGD VTNLVTGLSN
     IKTLHLSPDS LEVFYFCCKS MPVFHNLLTL SFESAKKEAG QCCHFSSISL LT
 
 
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