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FBL3_ARATH
ID   FBL3_ARATH              Reviewed;         665 AA.
AC   Q8RWU5; Q8LCI1; Q9M004;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=F-box/LRR-repeat protein 3;
GN   Name=FBL3; OrderedLocusNames=At5g01720; ORFNames=F7A7.240;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130714; DOI=10.1038/35048507;
RA   Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA   Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA   Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA   Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA   O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA   Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA   Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA   Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA   Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA   Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA   Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA   Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA   Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA   Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA   Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA   McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA   Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA   Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA   Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA   Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA   Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA   Bevan M., Fransz P.F.;
RT   "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL   Nature 408:823-826(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA   Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA   Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA   Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA   Shinozaki K.;
RT   "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL   Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 592-665.
RA   Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [6]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=11077244; DOI=10.1016/s1360-1385(00)01769-6;
RA   Xiao W., Jang J.-C.;
RT   "F-box proteins in Arabidopsis.";
RL   Trends Plant Sci. 5:454-457(2000).
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAB82288.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AL161946; CAB82288.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002688; AED90382.1; -; Genomic_DNA.
DR   EMBL; AY091103; AAM14053.1; -; mRNA.
DR   EMBL; AY122938; AAM67471.1; -; mRNA.
DR   EMBL; AK229588; BAF01436.1; -; mRNA.
DR   EMBL; AY086589; AAM67364.1; -; mRNA.
DR   PIR; T48193; T48193.
DR   RefSeq; NP_568094.2; NM_120250.4.
DR   AlphaFoldDB; Q8RWU5; -.
DR   STRING; 3702.AT5G01720.1; -.
DR   PaxDb; Q8RWU5; -.
DR   PRIDE; Q8RWU5; -.
DR   EnsemblPlants; AT5G01720.1; AT5G01720.1; AT5G01720.
DR   GeneID; 831688; -.
DR   Gramene; AT5G01720.1; AT5G01720.1; AT5G01720.
DR   KEGG; ath:AT5G01720; -.
DR   Araport; AT5G01720; -.
DR   TAIR; locus:2149805; AT5G01720.
DR   eggNOG; KOG1947; Eukaryota.
DR   HOGENOM; CLU_016072_3_1_1; -.
DR   InParanoid; Q8RWU5; -.
DR   OMA; FNMRTRV; -.
DR   OrthoDB; 1282076at2759; -.
DR   PhylomeDB; Q8RWU5; -.
DR   PRO; PR:Q8RWU5; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q8RWU5; baseline and differential.
DR   Genevisible; Q8RWU5; AT.
DR   GO; GO:0005634; C:nucleus; IDA:TAIR.
DR   GO; GO:0019005; C:SCF ubiquitin ligase complex; IPI:TAIR.
DR   GO; GO:0016567; P:protein ubiquitination; IMP:TAIR.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:TAIR.
DR   Gene3D; 3.80.10.10; -; 3.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   Pfam; PF13516; LRR_6; 4.
DR   SMART; SM00367; LRR_CC; 18.
PE   2: Evidence at transcript level;
KW   Leucine-rich repeat; Reference proteome; Repeat.
FT   CHAIN           1..665
FT                   /note="F-box/LRR-repeat protein 3"
FT                   /id="PRO_0000272247"
FT   DOMAIN          11..60
FT                   /note="F-box"
FT   REPEAT          61..81
FT                   /note="LRR 1"
FT   REPEAT          82..108
FT                   /note="LRR 2"
FT   REPEAT          109..134
FT                   /note="LRR 3"
FT   REPEAT          135..159
FT                   /note="LRR 4"
FT   REPEAT          160..185
FT                   /note="LRR 5"
FT   REPEAT          186..211
FT                   /note="LRR 6"
FT   REPEAT          214..235
FT                   /note="LRR 7"
FT   REPEAT          236..261
FT                   /note="LRR 8"
FT   REPEAT          262..287
FT                   /note="LRR 9"
FT   REPEAT          288..312
FT                   /note="LRR 10"
FT   REPEAT          313..338
FT                   /note="LRR 11"
FT   REPEAT          339..364
FT                   /note="LRR 12"
FT   REPEAT          365..390
FT                   /note="LRR 13"
FT   REPEAT          391..416
FT                   /note="LRR 14"
FT   REPEAT          419..440
FT                   /note="LRR 15"
FT   REPEAT          441..466
FT                   /note="LRR 16"
FT   REPEAT          467..492
FT                   /note="LRR 17"
FT   REPEAT          493..517
FT                   /note="LRR 18"
FT   REPEAT          518..543
FT                   /note="LRR 19"
FT   REPEAT          544..569
FT                   /note="LRR 20"
FT   REPEAT          594..619
FT                   /note="LRR 21"
SQ   SEQUENCE   665 AA;  72275 MW;  2FB18DD53FE1E54A CRC64;
     MKKVKQIRVL KPFDLLSEEL VFIILDLISP NPSDLKSFSL TCKSFYQLES KHRGSLKPLR
     SDYLPRILTR YRNTTDLDLT FCPRVTDYAL SVVGCLSGPT LRSLDLSRSG SFSAAGLLRL
     ALKCVNLVEI DLSNATEMRD ADAAVVAEAR SLERLKLGRC KMLTDMGIGC IAVGCKKLNT
     VSLKWCVGVG DLGVGLLAVK CKDIRTLDLS YLPITGKCLH DILKLQHLEE LLLEGCFGVD
     DDSLKSLRHD CKSLKKLDAS SCQNLTHRGL TSLLSGAGYL QRLDLSHCSS VISLDFASSL
     KKVSALQSIR LDGCSVTPDG LKAIGTLCNS LKEVSLSKCV SVTDEGLSSL VMKLKDLRKL
     DITCCRKLSR VSITQIANSC PLLVSLKMES CSLVSREAFW LIGQKCRLLE ELDLTDNEID
     DEGLKSISSC LSLSSLKLGI CLNITDKGLS YIGMGCSNLR ELDLYRSVGI TDVGISTIAQ
     GCIHLETINI SYCQDITDKS LVSLSKCSLL QTFESRGCPN ITSQGLAAIA VRCKRLAKVD
     LKKCPSINDA GLLALAHFSQ NLKQINVSDT AVTEVGLLSL ANIGCLQNIA VVNSSGLRPS
     GVAAALLGCG GLRKAKLHAS LRSLLPLSLI HHLEARGCAF LWKDNTLQAE LDPKYWKQQL
     EEMAP
 
 
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