FBL42_ARATH
ID FBL42_ARATH Reviewed; 481 AA.
AC Q84W80; C0Z2J3; Q0WMB7; Q9SRP0;
DT 03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-SEP-2009, sequence version 2.
DT 25-MAY-2022, entry version 111.
DE RecName: Full=F-box/LRR-repeat protein At3g03360;
GN OrderedLocusNames=At3g03360; ORFNames=T21P5.22;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
RC STRAIN=cv. Columbia;
RX PubMed=19423640; DOI=10.1093/dnares/dsp009;
RA Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M.,
RA Shinozaki K.;
RT "Analysis of multiple occurrences of alternative splicing events in
RT Arabidopsis thaliana using novel sequenced full-length cDNAs.";
RL DNA Res. 16:155-164(2009).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-207 (ISOFORM 2).
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=3;
CC IsoId=Q84W80-3; Sequence=Displayed;
CC Name=1;
CC IsoId=Q84W80-1; Sequence=VSP_037952, VSP_037953;
CC Name=2;
CC IsoId=Q84W80-2; Sequence=VSP_024105, VSP_037951;
CC -!- MISCELLANEOUS: [Isoform 1]: May be due to an intron retention.
CC {ECO:0000305}.
CC -!- MISCELLANEOUS: [Isoform 2]: Incomplete sequence. {ECO:0000305}.
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DR EMBL; AC009895; AAF01596.1; -; Genomic_DNA.
DR EMBL; CP002686; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BT004131; AAO42153.1; -; mRNA.
DR EMBL; AK318807; BAH56922.1; -; mRNA.
DR EMBL; AK229563; BAF01415.1; -; mRNA.
DR EMBL; AK229911; BAF01739.1; -; mRNA.
DR AlphaFoldDB; Q84W80; -.
DR BioGRID; 6605; 16.
DR STRING; 3702.AT3G03360.1; -.
DR PaxDb; Q84W80; -.
DR PRIDE; Q84W80; -.
DR EnsemblPlants; AT3G03360.1; AT3G03360.1; AT3G03360.
DR Gramene; AT3G03360.1; AT3G03360.1; AT3G03360.
DR Araport; AT3G03360; -.
DR TAIR; locus:2099644; AT3G03360.
DR eggNOG; ENOG502T15N; Eukaryota.
DR HOGENOM; CLU_010721_5_0_1; -.
DR InParanoid; Q84W80; -.
DR PhylomeDB; Q84W80; -.
DR PRO; PR:Q84W80; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q84W80; baseline and differential.
DR Genevisible; Q84W80; AT.
DR GO; GO:0005737; C:cytoplasm; IDA:TAIR.
DR Gene3D; 3.80.10.10; -; 1.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR044997; F-box_plant.
DR InterPro; IPR013101; Leu-rich_rpt_2.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR32153; PTHR32153; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF07723; LRR_2; 1.
DR SMART; SM00256; FBOX; 1.
DR SUPFAM; SSF81383; SSF81383; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Leucine-rich repeat; Reference proteome; Repeat.
FT CHAIN 1..481
FT /note="F-box/LRR-repeat protein At3g03360"
FT /id="PRO_0000281943"
FT DOMAIN 36..84
FT /note="F-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT REPEAT 118..145
FT /note="LRR 1"
FT REPEAT 196..221
FT /note="LRR 2"
FT REPEAT 295..320
FT /note="LRR 3"
FT REPEAT 350..375
FT /note="LRR 4"
FT REPEAT 413..439
FT /note="LRR 5"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..23
FT /note="MEKESQENSTRPDASSTVFSSSK -> MWVMRYLYKLQ (in isoform
FT 2)"
FT /evidence="ECO:0000303|Ref.5"
FT /id="VSP_024105"
FT VAR_SEQ 208..481
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.5"
FT /id="VSP_037951"
FT VAR_SEQ 386..391
FT /note="EEHIDI -> VIMNIP (in isoform 1)"
FT /evidence="ECO:0000303|PubMed:14593172"
FT /id="VSP_037952"
FT VAR_SEQ 392..481
FT /note="Missing (in isoform 1)"
FT /evidence="ECO:0000303|PubMed:14593172"
FT /id="VSP_037953"
SQ SEQUENCE 481 AA; 54948 MW; BC857035ED51C70D CRC64;
MEKESQENST RPDASSTVFS SSKSTCASPS YLKEAGDLIS RLPDDILQLI LSYLPTRLAI
KTSVLSRRWR HVWSDTWSLS FHRDRPDAPC INRILDRYRA PKMMSFRICS CCRAACISRP
DTHADIDSWI NFAMSRNVEN LSLYLDEDKY DIPEFLYINS SLKQLYLDFG CKKDFISLNP
KCSVSWTSLK NLSLYHCNIS DESIAIILSG CPILESLLLF FCKKLKVLDL SKSPRLITLE
ITRRCRMEPT QLVAPHIRCL RLINSEKPCA LVDVSSLSQA ELDITAYAIV DNKLEADFHQ
TMVVKMLEKC QNVEKLTLGA NFLKMLSLAE LRGVSFPKLK AKALILETMI SRYVIHGIVK
VLQNSPDLKK LTIHPMGSAG SYPIPEEHID IYLDSHGLNW DPSWSSEFKN TSRRNVESKQ
VASFLQLVLK TISTLELIVA RLEGYIKGRR FVELRQMVPM LPRNNDVSIV LSSRRKRFRV
T
