FBL8_ARATH
ID FBL8_ARATH Reviewed; 554 AA.
AC Q9S9X4;
DT 23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 125.
DE RecName: Full=Putative F-box/LRR-repeat protein 8;
GN Name=FBL8; Synonyms=FBL24; OrderedLocusNames=At4g07400; ORFNames=F28D6.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11077244; DOI=10.1016/s1360-1385(00)01769-6;
RA Xiao W., Jang J.-C.;
RT "F-box proteins in Arabidopsis.";
RL Trends Plant Sci. 5:454-457(2000).
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DR EMBL; AF147262; AAD48947.1; -; Genomic_DNA.
DR EMBL; AL161505; CAB81110.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE82565.1; -; Genomic_DNA.
DR PIR; B85072; B85072.
DR RefSeq; NP_567316.1; NM_116812.2.
DR AlphaFoldDB; Q9S9X4; -.
DR SMR; Q9S9X4; -.
DR BioGRID; 11477; 1.
DR STRING; 3702.AT4G07400.1; -.
DR iPTMnet; Q9S9X4; -.
DR PaxDb; Q9S9X4; -.
DR PRIDE; Q9S9X4; -.
DR EnsemblPlants; AT4G07400.1; AT4G07400.1; AT4G07400.
DR GeneID; 826171; -.
DR Gramene; AT4G07400.1; AT4G07400.1; AT4G07400.
DR KEGG; ath:AT4G07400; -.
DR Araport; AT4G07400; -.
DR TAIR; locus:2124372; AT4G07400.
DR eggNOG; KOG1947; Eukaryota.
DR HOGENOM; CLU_016072_4_0_1; -.
DR InParanoid; Q9S9X4; -.
DR OMA; HRCDEIS; -.
DR OrthoDB; 1027299at2759; -.
DR PhylomeDB; Q9S9X4; -.
DR PRO; PR:Q9S9X4; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9S9X4; baseline and differential.
DR Genevisible; Q9S9X4; AT.
DR GO; GO:0019005; C:SCF ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; ISS:TAIR.
DR GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR Gene3D; 3.80.10.10; -; 2.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF13516; LRR_6; 2.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00367; LRR_CC; 6.
DR SUPFAM; SSF81383; SSF81383; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 4: Predicted;
KW Leucine-rich repeat; Reference proteome; Repeat.
FT CHAIN 1..554
FT /note="Putative F-box/LRR-repeat protein 8"
FT /id="PRO_0000272249"
FT DOMAIN 71..117
FT /note="F-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT REPEAT 119..144
FT /note="LRR 1"
FT REPEAT 148..173
FT /note="LRR 2"
FT REPEAT 174..199
FT /note="LRR 3"
FT REPEAT 205..224
FT /note="LRR 4"
FT REPEAT 250..275
FT /note="LRR 5"
FT REPEAT 301..325
FT /note="LRR 6"
FT REPEAT 326..351
FT /note="LRR 7"
FT REPEAT 354..379
FT /note="LRR 8"
FT REPEAT 383..404
FT /note="LRR 9"
FT REPEAT 405..428
FT /note="LRR 10"
FT REPEAT 430..455
FT /note="LRR 11"
FT REPEAT 456..480
FT /note="LRR 12"
SQ SEQUENCE 554 AA; 61005 MW; F1E73FDC3B09206C CRC64;
MNIYIFSKEK KRKKVVCDNL SKTRGSRREH CEPHRRRMGQ STSKFRRSKT TFTSPVLPNL
REQNSGADEP YDYISNLPDE CLSLIFQSLT CADLKRCSLV CRRWLTIEGQ CRHRLSLKAQ
SDLISVIPSL FTRFDSVTKL VLRSDRRSLG ICDNAFVMIS VRCRNLTRLK LRGCPEISDL
GIIGFTENCR SLKKVSFGSC GFGVKGMNAL LNTCLGLEEL SVKRLRGIGA GAELIGPGGA
AGSLKVICLK ELHNGQCFAP LLSGAKGLRI LKIFRCSGDW DRVFEAVRDK VNAIVEIHLE
RIQMSDLGLT ALSKCSGVEV LHLVKTPDCT NVGLALVAER CKLLRKLHID GWKTNRIGDE
GLIVVAKYCW NLQELVLIGV NPTKLSLEAI VSNCLNLERL ALCGSDTVGD TELCCIAEKC
LALRKLCIKN CPITDDGIKA LGNGCPNLLK VKVKKCRGVT TQGADLLRKR RALLVVNLDA
PETPIVEGSV GEGGAQENAV EFPPSRLQIP TIGLASGSTS RSSSFKLRLG FLSQRNFVSC
ALRRLGSRSR SRNE
