ID   FBL91_ARATH             Reviewed;         529 AA.
AC   Q9FMV0; F4KAR0; Q8GX97;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=F-box/LRR-repeat protein At5g63520;
GN   OrderedLocusNames=At5g63520; ORFNames=MLE2.15;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9501997; DOI=10.1093/dnares/4.6.401;
RA   Nakamura Y., Sato S., Kaneko T., Kotani H., Asamizu E., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. III. Sequence
RT   features of the regions of 1,191,918 bp covered by seventeen physically
RT   assigned P1 clones.";
RL   DNA Res. 4:401-414(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 5-529.
RC   STRAIN=cv. Columbia;
RX   PubMed=11910074; DOI=10.1126/science.1071006;
RA   Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA   Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA   Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA   Shinagawa A., Shinozaki K.;
RT   "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL   Science 296:141-145(2002).
CC   -!- CAUTION: It is uncertain whether Met-1 or Met-11 is the initiator.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAC42965.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; AB007649; BAB08817.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED97762.2; -; Genomic_DNA.
DR   EMBL; AK118351; BAC42965.1; ALT_FRAME; mRNA.
DR   RefSeq; NP_201157.4; NM_125747.4.
DR   AlphaFoldDB; Q9FMV0; -.
DR   BioGRID; 21713; 6.
DR   STRING; 3702.AT5G63520.1; -.
DR   PaxDb; Q9FMV0; -.
DR   PRIDE; Q9FMV0; -.
DR   ProteomicsDB; 222439; -.
DR   EnsemblPlants; AT5G63520.1; AT5G63520.1; AT5G63520.
DR   GeneID; 836471; -.
DR   Gramene; AT5G63520.1; AT5G63520.1; AT5G63520.
DR   KEGG; ath:AT5G63520; -.
DR   Araport; AT5G63520; -.
DR   eggNOG; ENOG502QT6J; Eukaryota.
DR   HOGENOM; CLU_038429_0_0_1; -.
DR   InParanoid; Q9FMV0; -.
DR   OMA; YGRGESF; -.
DR   OrthoDB; 437968at2759; -.
DR   PhylomeDB; Q9FMV0; -.
DR   PRO; PR:Q9FMV0; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FMV0; baseline and differential.
DR   Genevisible; Q9FMV0; AT.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   GO; GO:0000209; P:protein polyubiquitination; IBA:GO_Central.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR019494; FIST_C.
DR   SMART; SM01204; FIST_C; 1.
DR   SUPFAM; SSF81383; SSF81383; 1.
PE   2: Evidence at transcript level;
KW   Leucine-rich repeat; Reference proteome; Repeat.
FT   CHAIN           1..529
FT                   /note="F-box/LRR-repeat protein At5g63520"
FT                   /id="PRO_0000281988"
FT   DOMAIN          31..78
FT                   /note="F-box"
FT   REPEAT          265..288
FT                   /note="LRR 1"
FT   REPEAT          418..441
FT                   /note="LRR 2"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   529 AA;  58304 MW;  6FE18EDA2D4ED3B1 CRC64;
     MAEVSLTKKE MTTKGKSENS KKMKTDMADM VPIAAMNEDL LHNILLRLPA KSFAFASCVN
     RFWSSVCNRI LSRPKMISAF SRNPDQLRAG EEVLDKVLSE PIRPQFVIAN ITCGNMEETL
     TLITERVGSR VPIIVSVVTG ILGKEACNDK AGEVRLHSTS DDELFDVANF AILLTIGYLP
     GMKVDIIPVI QAKGESGAEM EDKFVMDIRN YMSMVSGHAA APACLILFAE DTHATEPVLH
     KLDYAMPAET VIVGGQIGEF LHKRGNEPRN VQLQKDDIRV LAGLIFARDR HRPAQAERIQ
     FDTAISNGMS SVDLRYKAAN VNVSLGPSCP STLLTAKRRG EAEVLDGDQI LDDIDNILEN
     YIWENDSYLG VIKRRKYSIG LEEKPKIMSS LVFHQVNGSD DQDLLVDGAG IKTGDQFQVY
     LPDLKVAEAA LNDVSAQLRN LKSKPNKPEV VGGFAFVGSC RGDSFFGCPN ADSSPFLENF
     PELPFGGIFC DGEIGRSLIL EEGEEKKEVS IQRFLHVYSS VYLIVSYTS