ID   3MGH_LACH4              Reviewed;         210 AA.
AC   A8YWM6;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=lhv_0124;
OS   Lactobacillus helveticus (strain DPC 4571).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=405566;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DPC 4571;
RX   PubMed=17993529; DOI=10.1128/jb.01295-07;
RA   Callanan M., Kaleta P., O'Callaghan J., O'Sullivan O., Jordan K.,
RA   McAuliffe O., Sangrador-Vegas A., Slattery L., Fitzgerald G.F.,
RA   Beresford T., Ross R.P.;
RT   "Genome sequence of Lactobacillus helveticus: an organism distinguished by
RT   selective gene loss and IS element expansion.";
RL   J. Bacteriol. 190:727-735(2008).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
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DR   EMBL; CP000517; ABX26388.1; -; Genomic_DNA.
DR   RefSeq; WP_012211263.1; NC_010080.1.
DR   AlphaFoldDB; A8YWM6; -.
DR   SMR; A8YWM6; -.
DR   STRING; 405566.lhv_0124; -.
DR   PRIDE; A8YWM6; -.
DR   EnsemblBacteria; ABX26388; ABX26388; lhv_0124.
DR   KEGG; lhe:lhv_0124; -.
DR   eggNOG; COG2094; Bacteria.
DR   HOGENOM; CLU_060471_2_0_9; -.
DR   OMA; VEAYHHT; -.
DR   Proteomes; UP000000790; Chromosome.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 1.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
DR   TIGRFAMs; TIGR00567; 3mg; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase.
FT   CHAIN           1..210
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_1000072494"
SQ   SEQUENCE   210 AA;  24079 MW;  1142831CC501C077 CRC64;
     MNYSDYFTNR PTDEITRDLV GRPLIYDNGK EKIGGYIVEA EAYMGKNDRT AHSYGGHRSP
     ANEGLYRRGG TIYIYAQRQY FFFDVACQEE NEPQGVLIRA IEPIWGIDTM IKNRSGKSGV
     LLTNGPAKMM QAFGIHDKNW NLHFLSDSPF KIDLEDDHRK PAQEIIADKR VGINQSDPVW
     ANKKLRYYVA GNPYVSDMKK RNYAKNNGWA