ID   FBPB_ACTPL              Reviewed;         687 AA.
AC   Q44123; Q44122;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Ferric transport system permease protein FbpB;
GN   Name=fbpB; Synonyms=afuB;
OS   Actinobacillus pleuropneumoniae (Haemophilus pleuropneumoniae).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Actinobacillus.
OX   NCBI_TaxID=715;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 27088 / DSM 13472 / CCM 5869 / S4074 / Serotype 1, and
RC   K17 / Serotype 5;
RX   PubMed=8807793; DOI=10.1111/j.1574-6968.1996.tb08452.x;
RA   Chin N., Frey J., Chang C.F., Chang Y.F.;
RT   "Identification of a locus involved in the utilization of iron by
RT   Actinobacillus pleuropneumoniae.";
RL   FEMS Microbiol. Lett. 143:1-6(1996).
CC   -!- FUNCTION: Part of the ABC transporter complex FbpABC (TC 3.A.1.10.1)
CC       involved in Fe(3+) ions import. Probably responsible for the
CC       translocation of the substrate across the membrane (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (FbpC),
CC       two transmembrane proteins (FbpB) and a solute-binding protein (FbpA).
CC       {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. FbpB subfamily. {ECO:0000305}.
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DR   EMBL; U04954; AAB17217.1; -; Genomic_DNA.
DR   EMBL; U05042; AAB05031.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q44123; -.
DR   SMR; Q44123; -.
DR   STRING; 228399.appser1_15270; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 2.
DR   Gene3D; 1.10.3720.10; -; 2.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   Pfam; PF00528; BPD_transp_1; 2.
DR   SUPFAM; SSF161098; SSF161098; 2.
DR   PROSITE; PS50928; ABC_TM1; 2.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Iron; Iron transport;
KW   Membrane; Repeat; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..687
FT                   /note="Ferric transport system permease protein FbpB"
FT                   /id="PRO_0000060015"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        85..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        192..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        226..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        271..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        318..338
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        347..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        378..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        425..445
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        450..472
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        484..504
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        517..537
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        538..558
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        594..614
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        620..640
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        649..669
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          188..393
FT                   /note="ABC transmembrane type-1 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          479..669
FT                   /note="ABC transmembrane type-1 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   687 AA;  75605 MW;  DFC6859BC2DA0FE2 CRC64;
     MDSITNKRSL FESSHFWILL SLIAFIALPS KALDYGLLES TADEFLDAMG WSSVNLTILW
     FLPLIGFWLL PSLKLSTETQ AKVELGLISF ILLFAFISAT IYKVSMGYSV IVLIATLTAL
     ATFAFAKLKM MQGDKFIIGA LLSIILLIFF FIVYPTVAIF ISMFYDGETF APEQVVRILG
     QGYIVRVISN SLFLSGFVGI VSTVFGLAFA LYTTRIAHRT AFIGKIFSIL PIVTPPFVVG
     LGVTLMLGRS GYVTEFLDTY FGFKDHNWLY GFNGIAIAQI LAFAPISFMI LDGALKSIHP
     SIEEASYTLR ANRYQTFYNI IFPLLRPALA NSFLIVFIQS LADFSNPLVL GGSFDVIATQ
     IYFYIAGSQL DYASASTLGS MLLIFSLLIF IVQYMWIGNR SYVTVSGKSY RGDVQDLPSG
     LKYTIIVMLG FWVVFNFALY GSIFYGSFTV NWGVDYTLTL NNYAMLFGQG LSDGAWPSLI
     NTMIYAGIAA PLTALFGLLI AYIVVRKDFQ GKKTLEFLTM LCFAVPGTVA GVSYILAFND
     APMYITGTGI IIIISMVMRD LPIGMRAAIA GLGQLDKSLD EASLSLKGSS LKTIWFIVFP
     LLKPALLSAL VTSFVRAMTT VSAIVFLVTA DTRVATAYIL NRVEDGEYGV AIAYGSILIV
     VMMAIILFFD WIVGDTRIPK SQAKKAD