FBPC2_PECAS
ID FBPC2_PECAS Reviewed; 346 AA.
AC Q6D2F6;
DT 01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Fe(3+) ions import ATP-binding protein FbpC 2 {ECO:0000255|HAMAP-Rule:MF_01706};
DE EC=7.2.2.7 {ECO:0000255|HAMAP-Rule:MF_01706};
GN Name=fbpC2 {ECO:0000255|HAMAP-Rule:MF_01706}; Synonyms=afuC2;
GN OrderedLocusNames=ECA3139;
OS Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia
OS carotovora subsp. atroseptica).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Pectobacteriaceae; Pectobacterium.
OX NCBI_TaxID=218491;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCRI 1043 / ATCC BAA-672;
RX PubMed=15263089; DOI=10.1073/pnas.0402424101;
RA Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J.,
RA Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K.,
RA Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J.,
RA Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Norbertczak H.,
RA Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S.,
RA Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K.;
RT "Genome sequence of the enterobacterial phytopathogen Erwinia carotovora
RT subsp. atroseptica and characterization of virulence factors.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004).
CC -!- FUNCTION: Part of the ABC transporter complex FbpABC involved in Fe(3+)
CC ions import. Responsible for energy coupling to the transport system.
CC {ECO:0000255|HAMAP-Rule:MF_01706}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + Fe(3+)(out) + H2O = ADP + Fe(3+)(in) + H(+) + phosphate;
CC Xref=Rhea:RHEA:12332, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:29034, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:456216; EC=7.2.2.7; Evidence={ECO:0000255|HAMAP-
CC Rule:MF_01706};
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (FbpC),
CC two transmembrane proteins (FbpB) and a solute-binding protein (FbpA).
CC {ECO:0000255|HAMAP-Rule:MF_01706}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01706}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01706}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Fe(3+) ion
CC importer (TC 3.A.1.10) family. {ECO:0000255|HAMAP-Rule:MF_01706}.
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DR EMBL; BX950851; CAG76038.1; -; Genomic_DNA.
DR RefSeq; WP_011094662.1; NC_004547.2.
DR AlphaFoldDB; Q6D2F6; -.
DR SMR; Q6D2F6; -.
DR STRING; 218491.ECA3139; -.
DR EnsemblBacteria; CAG76038; CAG76038; ECA3139.
DR GeneID; 57209824; -.
DR KEGG; eca:ECA3139; -.
DR PATRIC; fig|218491.5.peg.3176; -.
DR eggNOG; COG3842; Bacteria.
DR HOGENOM; CLU_000604_1_1_6; -.
DR OMA; GLRENMR; -.
DR OrthoDB; 1200451at2; -.
DR Proteomes; UP000007966; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0015408; F:ABC-type ferric iron transporter activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR CDD; cd03259; ABC_Carb_Solutes_like; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR015853; ABC_transpr_FbpC.
DR InterPro; IPR030287; FbpC.
DR InterPro; IPR008995; Mo/tungstate-bd_C_term_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013611; Transp-assoc_OB_typ2.
DR PANTHER; PTHR24220:SF675; PTHR24220:SF675; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF08402; TOBE_2; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF50331; SSF50331; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS51242; FBPC; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell inner membrane; Cell membrane; Ion transport; Iron;
KW Iron transport; Membrane; Nucleotide-binding; Reference proteome;
KW Translocase; Transport.
FT CHAIN 1..346
FT /note="Fe(3+) ions import ATP-binding protein FbpC 2"
FT /id="PRO_0000092350"
FT DOMAIN 2..234
FT /note="ABC transporter"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01706"
FT BINDING 34..41
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01706"
SQ SEQUENCE 346 AA; 37468 MW; BF05D3EFF35DC5F0 CRC64;
MLELHRVSKS FNGRTVLSDI HLTLENSRRT AIVGPSGSGK TTLLRLIAGF ETPDTGVITL
NGQTLCDNGF SVPAHQRRIG YVPQDGALFP HLCIADNIAF GLKGSKAEKQ KRVDELMALV
SLPTHLQKHS PHEISGGQQQ RVALARALAQ RPALMLLDEP FSALDTGLRA ATRKAVMDVL
QQANVASILV THDQGEALSF ADRVVVMREG QLSQSGSPWA LYHQPNSEDI ATFLGETLIL
NAQIDGGKAD CLLGRIAVDR PTANGRVRIM LRPEQITIQD TEITSTAHMR ATIRNVEFSG
FVSTLTLRIH NAEADVIELK TVSHAAFIVG QQVSLSVNGA AHVFSQ
