ID   FBPC_NEIGO              Reviewed;         352 AA.
AC   Q50966;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Fe(3+) ions import ATP-binding protein FbpC {ECO:0000255|HAMAP-Rule:MF_01706};
DE            EC=7.2.2.7 {ECO:0000255|HAMAP-Rule:MF_01706};
GN   Name=fbpC {ECO:0000255|HAMAP-Rule:MF_01706};
OS   Neisseria gonorrhoeae.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=485;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 33084 / F62 / M-1914;
RX   PubMed=2110241; DOI=10.1084/jem.171.5.1535;
RA   Berish S.A., Mietzner T.A., Mayer L.W., Genco C.A., Holloway B.P.,
RA   Morse S.A.;
RT   "Molecular cloning and characterization of the structural gene for the
RT   major iron-regulated protein expressed by Neisseria gonorrhoeae.";
RL   J. Exp. Med. 171:1535-1546(1990).
CC   -!- FUNCTION: Part of the ABC transporter complex FbpABC involved in Fe(3+)
CC       ions import. Responsible for energy coupling to the transport system.
CC       {ECO:0000255|HAMAP-Rule:MF_01706}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + Fe(3+)(out) + H2O = ADP + Fe(3+)(in) + H(+) + phosphate;
CC         Xref=Rhea:RHEA:12332, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:29034, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:456216; EC=7.2.2.7; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_01706};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (FbpC),
CC       two transmembrane proteins (FbpB) and a solute-binding protein (FbpA).
CC       {ECO:0000255|HAMAP-Rule:MF_01706}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01706}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01706}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Fe(3+) ion
CC       importer (TC 3.A.1.10) family. {ECO:0000255|HAMAP-Rule:MF_01706}.
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DR   EMBL; U33937; AAB63561.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q50966; -.
DR   SMR; Q50966; -.
DR   DIP; DIP-48300N; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015408; F:ABC-type ferric iron transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd03259; ABC_Carb_Solutes_like; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR015853; ABC_transpr_FbpC.
DR   InterPro; IPR041230; FbpC_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF17845; FbpC_C_terminal; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51242; FBPC; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell inner membrane; Cell membrane; Ion transport; Iron;
KW   Iron transport; Membrane; Nucleotide-binding; Translocase; Transport.
FT   CHAIN           1..352
FT                   /note="Fe(3+) ions import ATP-binding protein FbpC"
FT                   /id="PRO_0000092355"
FT   DOMAIN          5..239
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01706"
FT   BINDING         37..44
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01706"
SQ   SEQUENCE   352 AA;  37857 MW;  E6DCAD987761D48B CRC64;
     MTAALHIGHL SKSFQNTPVL NDISLSLDPG EILFIIGASG CGKTTLLRCL AGFEQPDSGE
     ISLSGKTIFS KNTNLPVRET TFGLPRTGRC SVPHLTVYRN IAYGLGNGKG RTAQERQRIE
     AMLELTGISE LAGRYPHELS GGQQQRVALA RALAPDPELI LLDEPFSALD EQLRRQIRED
     MIAALRANGK SAVFVSHDRE EALQYADRIA VMKQGRILQT ASPHELYRQP ADLDAVLFIG
     EGIVFPAALN ADGTADCRLG RLPVQSGAPA GTRGTLLIRP EQFSLHPHSA PVVSIHAVVL
     KTTPKARYTE ISLRAGQTVL TLNLPSAPTL SDGISAVLHL DGPALFFPGN TL