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FBPC_PHOPR
ID   FBPC_PHOPR              Reviewed;         351 AA.
AC   Q6LKD4;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 2.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Fe(3+) ions import ATP-binding protein FbpC {ECO:0000255|HAMAP-Rule:MF_01706};
DE            EC=7.2.2.7 {ECO:0000255|HAMAP-Rule:MF_01706};
GN   Name=fbpC {ECO:0000255|HAMAP-Rule:MF_01706}; OrderedLocusNames=PBPRB0373;
OS   Photobacterium profundum (strain SS9).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Photobacterium.
OX   NCBI_TaxID=298386;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1253 / SS9;
RX   PubMed=15746425; DOI=10.1126/science.1103341;
RA   Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M.,
RA   Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C.,
RA   Bartlett D.H., Valle G.;
RT   "Life at depth: Photobacterium profundum genome sequence and expression
RT   analysis.";
RL   Science 307:1459-1461(2005).
CC   -!- FUNCTION: Part of the ABC transporter complex FbpABC involved in Fe(3+)
CC       ions import. Responsible for energy coupling to the transport system.
CC       {ECO:0000255|HAMAP-Rule:MF_01706}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + Fe(3+)(out) + H2O = ADP + Fe(3+)(in) + H(+) + phosphate;
CC         Xref=Rhea:RHEA:12332, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:29034, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:456216; EC=7.2.2.7; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_01706};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (FbpC),
CC       two transmembrane proteins (FbpB) and a solute-binding protein (FbpA).
CC       {ECO:0000255|HAMAP-Rule:MF_01706}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01706}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01706}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Fe(3+) ion
CC       importer (TC 3.A.1.10) family. {ECO:0000255|HAMAP-Rule:MF_01706}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAG22246.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CR378676; CAG22246.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_011220457.1; NC_006371.1.
DR   AlphaFoldDB; Q6LKD4; -.
DR   SMR; Q6LKD4; -.
DR   STRING; 298386.PBPRB0373; -.
DR   EnsemblBacteria; CAG22246; CAG22246; PBPRB0373.
DR   KEGG; ppr:PBPRB0373; -.
DR   eggNOG; COG3842; Bacteria.
DR   HOGENOM; CLU_000604_1_1_6; -.
DR   OrthoDB; 1200451at2; -.
DR   Proteomes; UP000000593; Chromosome 2.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0015408; F:ABC-type ferric iron transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR030287; FbpC.
DR   InterPro; IPR008995; Mo/tungstate-bd_C_term_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013611; Transp-assoc_OB_typ2.
DR   PANTHER; PTHR24220:SF675; PTHR24220:SF675; 1.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF08402; TOBE_2; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF50331; SSF50331; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51242; FBPC; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell inner membrane; Cell membrane; Ion transport; Iron;
KW   Iron transport; Membrane; Nucleotide-binding; Reference proteome;
KW   Translocase; Transport.
FT   CHAIN           1..351
FT                   /note="Fe(3+) ions import ATP-binding protein FbpC"
FT                   /id="PRO_0000092360"
FT   DOMAIN          7..237
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01706"
FT   BINDING         39..46
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01706"
SQ   SEQUENCE   351 AA;  38951 MW;  A9FB873F3CE690C4 CRC64;
     MENDNFVVLK NVCKRFGDNT VINNLDLEIK KGSLVTLLGP SGCGKTTVLR LVAGLEKPTS
     GQIFIDGEDV TNTSIQQRDI CMVFQSYALF PHLSLYDNVG YGLKMLKLPA AEIKQRVDDA
     LKLVDLSGMG DRFVDQISGG QQQRIALARA LVLKPKVLLF DEPLSNLDAN LRRSMRETIR
     DLQQRFNITS LYVTHDQTEA FAVSDTVIVM KDGEIMQQGS PDDLYKTPSS MFMANFMGDA
     NIFTGRYDDG QLNINGYCIP ADPEVVQGKA EGDYQIGVRP EAILLTSEGE PSQQCIVNNV
     VYMGSMYEVA VTWHDQELLL QLNSSQFDAN LSDHAYLTIN PTGIFLLPFD A
 
 
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