ID   FBPC_STRCO              Reviewed;         348 AA.
AC   O86751;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   03-AUG-2022, entry version 136.
DE   RecName: Full=Fe(3+) ions import ATP-binding protein FbpC {ECO:0000255|HAMAP-Rule:MF_01706};
DE            EC=7.2.2.7 {ECO:0000255|HAMAP-Rule:MF_01706};
GN   Name=fbpC {ECO:0000255|HAMAP-Rule:MF_01706}; OrderedLocusNames=SCO5648;
GN   ORFNames=SC6A9.19c;
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145;
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H.,
RA   Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
CC   -!- FUNCTION: Part of the ABC transporter complex FbpABC involved in Fe(3+)
CC       ions import. Responsible for energy coupling to the transport system.
CC       {ECO:0000255|HAMAP-Rule:MF_01706}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + Fe(3+)(out) + H2O = ADP + Fe(3+)(in) + H(+) + phosphate;
CC         Xref=Rhea:RHEA:12332, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:29034, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:456216; EC=7.2.2.7; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_01706};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (FbpC),
CC       two transmembrane proteins (FbpB) and a solute-binding protein (FbpA).
CC       {ECO:0000255|HAMAP-Rule:MF_01706}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01706};
CC       Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01706}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Fe(3+) ion
CC       importer (TC 3.A.1.10) family. {ECO:0000255|HAMAP-Rule:MF_01706}.
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DR   EMBL; AL939124; CAA19904.1; -; Genomic_DNA.
DR   PIR; T35450; T35450.
DR   RefSeq; NP_629778.1; NC_003888.3.
DR   RefSeq; WP_011030362.1; NZ_VNID01000024.1.
DR   AlphaFoldDB; O86751; -.
DR   SMR; O86751; -.
DR   STRING; 100226.SCO5648; -.
DR   GeneID; 1101087; -.
DR   KEGG; sco:SCO5648; -.
DR   PATRIC; fig|100226.15.peg.5731; -.
DR   eggNOG; COG3842; Bacteria.
DR   HOGENOM; CLU_000604_1_1_11; -.
DR   InParanoid; O86751; -.
DR   OMA; HEIVCVL; -.
DR   PhylomeDB; O86751; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0015408; F:ABC-type ferric iron transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR008995; Mo/tungstate-bd_C_term_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013611; Transp-assoc_OB_typ2.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF08402; TOBE_2; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF50331; SSF50331; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51242; FBPC; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Ion transport; Iron; Iron transport; Membrane;
KW   Nucleotide-binding; Reference proteome; Translocase; Transport.
FT   CHAIN           1..348
FT                   /note="Fe(3+) ions import ATP-binding protein FbpC"
FT                   /id="PRO_0000092366"
FT   DOMAIN          6..236
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01706"
FT   BINDING         38..45
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01706"
SQ   SEQUENCE   348 AA;  36571 MW;  DF4DC79D6FCCDBC0 CRC64;
     MPPSLLSLEG ATVRFGGRAV LDDVGLGVAE HEVVCVLGPS GSGKSTLLRA VAGLQPLDAG
     RVTLDGRDQS GVPAHKREVG LMFQDHQLFP QRDVAGNIAF GPRMRGASRA EQQARVAELL
     QLVGLPGAAR RSVAALSGGE QQRVALARAL APRPRLLMLD EPLGQLDRSL RERLVVELRE
     LFGRLGTTVL AVTHDQGEAF ALADRVVVMR DGRIAQSGTP LEVWQRPADA FVARFLGFEN
     VAEASVAGQA ADTPWGKVPV PEDAPQGTRT VLVRPAGVRV VPADEGLRCT VTARTFRGTH
     VAVHLQPEGA PRLEAACALR AAPEVGAAVG VEFDAADVVV LGGSGVPE