ID   3MGH_LACJO              Reviewed;         208 AA.
AC   Q74LU5;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=LJ_0088;
OS   Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=257314;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CNCM I-1225 / La1 / NCC 533;
RX   PubMed=14983040; DOI=10.1073/pnas.0307327101;
RA   Pridmore R.D., Berger B., Desiere F., Vilanova D., Barretto C.,
RA   Pittet A.-C., Zwahlen M.-C., Rouvet M., Altermann E., Barrangou R.,
RA   Mollet B., Mercenier A., Klaenhammer T., Arigoni F., Schell M.A.;
RT   "The genome sequence of the probiotic intestinal bacterium Lactobacillus
RT   johnsonii NCC 533.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:2512-2517(2004).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
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DR   EMBL; AE017198; AAS08070.1; -; Genomic_DNA.
DR   RefSeq; WP_011161321.1; NC_005362.1.
DR   AlphaFoldDB; Q74LU5; -.
DR   SMR; Q74LU5; -.
DR   STRING; 257314.LJ_0088; -.
DR   EnsemblBacteria; AAS08070; AAS08070; LJ_0088.
DR   KEGG; ljo:LJ_0088; -.
DR   eggNOG; COG2094; Bacteria.
DR   HOGENOM; CLU_060471_2_0_9; -.
DR   OMA; VEAYHHT; -.
DR   Proteomes; UP000000581; Chromosome.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 1.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
DR   TIGRFAMs; TIGR00567; 3mg; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase; Reference proteome.
FT   CHAIN           1..208
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_0000265028"
SQ   SEQUENCE   208 AA;  23353 MW;  9DF496A47F8C772D CRC64;
     MNYTEFFTNR STSEISKDLL GRTLSYNNGE EILSGTIVEA EAYVGVKDRA AHSYGGRRSP
     ANEGLYRPGG SLYIYSQRQY FFFDVSCQEE GEPQGVLIRA IDPLTGIDTM IKNRSGKTGP
     LLTNGPGKMM QALGITSRKW DLVDLNDSPF DIDIDHKREI EEIVALPRVG INQSDPEWAQ
     KKLRFIVSGN PYVSDIKKKD IKKNHGFI