ID   FBX12_ARATH             Reviewed;         404 AA.
AC   P0C2C9; Q9FYI0;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=F-box only protein 12;
GN   Name=FBX12; OrderedLocusNames=At1g30935; ORFNames=F17F8.20;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=11077244; DOI=10.1016/s1360-1385(00)01769-6;
RA   Xiao W., Jang J.-C.;
RT   "F-box proteins in Arabidopsis.";
RL   Trends Plant Sci. 5:454-457(2000).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF98190.1; Type=Erroneous gene model prediction; Note=The predicted gene At1g30930 has been split into 2 genes: At1g30930 and At1g30935.; Evidence={ECO:0000305};
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DR   EMBL; AC000107; AAF98190.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; P0C2C9; -.
DR   PeptideAtlas; P0C2C9; -.
DR   PRIDE; P0C2C9; -.
DR   Araport; AT1G30935; -.
DR   InParanoid; P0C2C9; -.
DR   PRO; PR:P0C2C9; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; P0C2C9; baseline.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR013187; F-box-assoc_dom_typ3.
DR   InterPro; IPR017451; F-box-assoc_interact_dom.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   Pfam; PF00646; F-box; 1.
DR   Pfam; PF08268; FBA_3; 1.
DR   SMART; SM00256; FBOX; 1.
DR   SUPFAM; SSF81383; SSF81383; 1.
DR   TIGRFAMs; TIGR01640; F_box_assoc_1; 1.
DR   PROSITE; PS50181; FBOX; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..404
FT                   /note="F-box only protein 12"
FT                   /id="PRO_0000273546"
FT   TRANSMEM        383..403
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          1..44
FT                   /note="F-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
SQ   SEQUENCE   404 AA;  46505 MW;  1C7E19FCCC7A2AEB CRC64;
     MKNSIPIDLI YEILSRLPAK SVARCRCVSK RWRSILRHQV FTELFLTRSN ARPRLLIGVQ
     QDGEWSFLST PQPQNRHESS SLVVAAADFH TKFSSGKSRH QCTYASGGSY SYLGFDPIDK
     EFKVLFMDTC DFIASKDEDH YILTLGTGEL KWRKIQCPFT HEPFWERICI NGVLYYSAYY
     SDSNGRSHLI ACFDVRSEKF NFIATKHRYD QLINYKGKLC GINLEYARHV GGFPVKLSMW
     VLEDVEKPEW SKHVYSLWTE SEVVKVNRNL SVSGMTATGD IVLSMEDATN PFYVFNFNPD
     RNTLQVQSVE IQGLGANRDH IACHAFVDYV EDFSVSDAVL QLKSSPLQQQ GQDTSHDLSK
     SVKNKQLDNY EFLANKLNHS VSLAILFCLF FLLFNYLIRL CWVR