FBX36_MOUSE
ID FBX36_MOUSE Reviewed; 188 AA.
AC Q9CQ24;
DT 16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=F-box only protein 36;
GN Name=Fbxo36;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Embryo, and Small intestine;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- FUNCTION: Substrate-recognition component of the SCF (SKP1-CUL1-F-box
CC protein)-type E3 ubiquitin ligase complex. {ECO:0000250}.
CC -!- SUBUNIT: Directly interacts with SKP1 and CUL1. {ECO:0000250}.
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DR EMBL; AK003856; BAB23040.1; -; mRNA.
DR EMBL; AK008324; BAB25602.1; -; mRNA.
DR EMBL; BC049581; AAH49581.1; -; mRNA.
DR CCDS; CCDS35634.1; -.
DR RefSeq; NP_079662.1; NM_025386.3.
DR AlphaFoldDB; Q9CQ24; -.
DR SMR; Q9CQ24; -.
DR STRING; 10090.ENSMUSP00000095276; -.
DR PhosphoSitePlus; Q9CQ24; -.
DR EPD; Q9CQ24; -.
DR PaxDb; Q9CQ24; -.
DR PRIDE; Q9CQ24; -.
DR ProteomicsDB; 270966; -.
DR Antibodypedia; 34398; 114 antibodies from 21 providers.
DR DNASU; 66153; -.
DR Ensembl; ENSMUST00000097672; ENSMUSP00000095276; ENSMUSG00000073633.
DR GeneID; 66153; -.
DR KEGG; mmu:66153; -.
DR UCSC; uc007btc.2; mouse.
DR CTD; 130888; -.
DR MGI; MGI:1289192; Fbxo36.
DR VEuPathDB; HostDB:ENSMUSG00000073633; -.
DR eggNOG; KOG1777; Eukaryota.
DR GeneTree; ENSGT00390000001015; -.
DR HOGENOM; CLU_108656_0_0_1; -.
DR InParanoid; Q9CQ24; -.
DR OMA; RFAKLCT; -.
DR OrthoDB; 1245866at2759; -.
DR PhylomeDB; Q9CQ24; -.
DR TreeFam; TF329337; -.
DR BioGRID-ORCS; 66153; 2 hits in 73 CRISPR screens.
DR ChiTaRS; Fbxo36; mouse.
DR PRO; PR:Q9CQ24; -.
DR Proteomes; UP000000589; Chromosome 1.
DR RNAct; Q9CQ24; protein.
DR Bgee; ENSMUSG00000073633; Expressed in gastrula and 179 other tissues.
DR Genevisible; Q9CQ24; MM.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR Pfam; PF00646; F-box; 1.
DR SUPFAM; SSF81383; SSF81383; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 1: Evidence at protein level;
KW Reference proteome; Ubl conjugation pathway.
FT CHAIN 1..188
FT /note="F-box only protein 36"
FT /id="PRO_0000119929"
FT DOMAIN 91..137
FT /note="F-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
SQ SEQUENCE 188 AA; 22075 MW; D4751CD060D0493C CRC64;
MASWLPETLF EIVGQGPAPS KDYYQLLITR TQIIFRWWKI SLRSEYRSAK PGETKESHED
FLDNSHLQVQ VAVVFGTKIL DYVFNLCEGK FDYLERLSDR LLLKIICYLD LEDIASLSQT
SSKFEKLCKS DLLWEQIVQS TCDTITPDMR ALAKNMGWRQ MFLTNNIQLQ RQTRKKKQRQ
ENQAEKLA
