ID   FBX39_BOVIN             Reviewed;         443 AA.
AC   Q32LM4;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=F-box only protein 39;
GN   Name=FBXO39;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Substrate-recognition component of the SCF (SKP1-CUL1-F-box
CC       protein)-type E3 ubiquitin ligase complex. {ECO:0000250}.
CC   -!- SUBUNIT: Directly interacts with SKP1 and CUL1. {ECO:0000250}.
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DR   EMBL; BC109511; AAI09512.1; -; mRNA.
DR   RefSeq; NP_001032702.1; NM_001037613.2.
DR   AlphaFoldDB; Q32LM4; -.
DR   SMR; Q32LM4; -.
DR   STRING; 9913.ENSBTAP00000024410; -.
DR   PaxDb; Q32LM4; -.
DR   PRIDE; Q32LM4; -.
DR   Ensembl; ENSBTAT00000024410; ENSBTAP00000024410; ENSBTAG00000018345.
DR   GeneID; 539103; -.
DR   KEGG; bta:539103; -.
DR   CTD; 162517; -.
DR   VEuPathDB; HostDB:ENSBTAG00000018345; -.
DR   VGNC; VGNC:28909; FBXO39.
DR   eggNOG; KOG1947; Eukaryota.
DR   GeneTree; ENSGT00510000048837; -.
DR   HOGENOM; CLU_050223_0_0_1; -.
DR   InParanoid; Q32LM4; -.
DR   OMA; KCILTTI; -.
DR   OrthoDB; 1046098at2759; -.
DR   TreeFam; TF321665; -.
DR   Proteomes; UP000009136; Chromosome 19.
DR   Bgee; ENSBTAG00000018345; Expressed in semen and 10 other tissues.
DR   GO; GO:0019005; C:SCF ubiquitin ligase complex; IBA:GO_Central.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR045048; FBXO31/39.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR10706; PTHR10706; 1.
DR   Pfam; PF12937; F-box-like; 1.
DR   SUPFAM; SSF81383; SSF81383; 1.
DR   PROSITE; PS50181; FBOX; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Ubl conjugation pathway.
FT   CHAIN           1..443
FT                   /note="F-box only protein 39"
FT                   /id="PRO_0000226719"
FT   DOMAIN          16..61
FT                   /note="F-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
SQ   SEQUENCE   443 AA;  52771 MW;  5B34514F2E350FC1 CRC64;
     MDEEDQLIQP QDQSCWATLP DVCLRRVFWW LGDRDRSRAA LVCRKWNQMM YSADLWRYRT
     ITFSGRPSRV HASEFESALW YVKKFGRYLE HLEIKFLNPY NAVLTKKFQV TMRGLLSCLG
     KSNNRLKSLS IQHLELDRLV WRNSIRSSFM KSLSFFLKKM GKHLNYLSLK GARLTTEQGC
     HILNALSYLR NESTVTELNI EDCFSHHLAV YSSPQFNKTM ATFRNLVSLT LNYNCISDEL
     LENLCDNNTG TLRTMNIKCH IHDPHGQVIW GMSWAKLARH ATSLKVNFFF ERVMKYERLA
     RILLQEIPIR SISLRSCYFS DPDWSMRPTL TDLLPTFRHT LQKLTFEFNN NHESLDEELH
     LLILSCRKLF YFKIWAFLDV KFVERILKSR EEGQCALRTL KVRIYTNRYE TNEEDRTLRE
     IYRKYRKLID SELNYFVIAY PMM