ID   FBX6_ARATH              Reviewed;         467 AA.
AC   Q9FZK1; Q8LEE1;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=F-box only protein 6;
GN   Name=FBX6; OrderedLocusNames=At1g27340; ORFNames=F17L21.13;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Shinn P., Chen H., Kim C.J., Quinitio C., Ecker J.R.;
RT   "Arabidopsis ORF clones.";
RL   Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=11077244; DOI=10.1016/s1360-1385(00)01769-6;
RA   Xiao W., Jang J.-C.;
RT   "F-box proteins in Arabidopsis.";
RL   Trends Plant Sci. 5:454-457(2000).
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DR   EMBL; AC004557; AAF99732.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE30808.1; -; Genomic_DNA.
DR   EMBL; AY085471; AAM62697.1; -; mRNA.
DR   EMBL; BT025325; ABF57281.1; -; mRNA.
DR   RefSeq; NP_564278.1; NM_102496.4.
DR   AlphaFoldDB; Q9FZK1; -.
DR   SMR; Q9FZK1; -.
DR   BioGRID; 24858; 7.
DR   IntAct; Q9FZK1; 7.
DR   STRING; 3702.AT1G27340.1; -.
DR   PaxDb; Q9FZK1; -.
DR   PRIDE; Q9FZK1; -.
DR   EnsemblPlants; AT1G27340.1; AT1G27340.1; AT1G27340.
DR   GeneID; 839623; -.
DR   Gramene; AT1G27340.1; AT1G27340.1; AT1G27340.
DR   KEGG; ath:AT1G27340; -.
DR   Araport; AT1G27340; -.
DR   TAIR; locus:2015974; AT1G27340.
DR   eggNOG; ENOG502QQ35; Eukaryota.
DR   HOGENOM; CLU_038778_2_1_1; -.
DR   InParanoid; Q9FZK1; -.
DR   OMA; ARTGYNS; -.
DR   OrthoDB; 1357499at2759; -.
DR   PhylomeDB; Q9FZK1; -.
DR   PRO; PR:Q9FZK1; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9FZK1; baseline and differential.
DR   Genevisible; Q9FZK1; AT.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IBA:GO_Central.
DR   GO; GO:0010305; P:leaf vascular tissue pattern formation; IMP:TAIR.
DR   GO; GO:0010928; P:regulation of auxin mediated signaling pathway; IMP:TAIR.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   GO; GO:0060776; P:simple leaf morphogenesis; IMP:TAIR.
DR   Gene3D; 2.120.10.80; -; 1.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   Pfam; PF00646; F-box; 1.
DR   SMART; SM00256; FBOX; 1.
DR   SUPFAM; SSF50965; SSF50965; 1.
DR   SUPFAM; SSF81383; SSF81383; 1.
DR   PROSITE; PS50181; FBOX; 1.
PE   2: Evidence at transcript level;
KW   Kelch repeat; Reference proteome; Repeat.
FT   CHAIN           1..467
FT                   /note="F-box only protein 6"
FT                   /id="PRO_0000273539"
FT   DOMAIN          114..163
FT                   /note="F-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT   REPEAT          163..211
FT                   /note="Kelch 1"
FT   REPEAT          252..305
FT                   /note="Kelch 2"
FT   REPEAT          406..456
FT                   /note="Kelch 3"
FT   CONFLICT        259
FT                   /note="S -> F (in Ref. 3; AAM62697)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   467 AA;  52822 MW;  7C16A78A3B026F34 CRC64;
     MEEELAMLRQ LIGQLQELLH NGSPPPPSSS SSLSSSSPSF LVLHHPQYQN GWCLPCIEDT
     SADDCCDIVM AGGKRPGIFK MLETVKPPVK RTRKERTQGK SCTEVDEISG NMDQEIWQEF
     PQDLFEDVVS RLPMATFFQF RAVCRKWNAL IDSDSFSRCF TELPQTIPWF YTITHENVNS
     GQVYDPSLKK WHHPIIPALP KKSIVLPMAS AGGLVCFLDI GHRNFYVSNP LTKSFRELPA
     RSFKVWSRVA VGMTLNGNST SHGYKVLWVG CEGEYEVYDS LSNVWTKRGT IPSNIKLPVL
     LNFKSQPVAI HSTLYFMLTD PEGILSYDMV SGKWKQFIIP GPPDLSDHTL AACGERLMLV
     GLLTKNAATC VCIWELQKMT LLWKEVDRMP NIWCLEFYGK HIRMNCLGNK GCLILLSLRS
     RQMNRLITYN AVTREWTKVP GCTVPRGRKR LWIACGTAFH PSPTARA