FCA1_CRIFA
ID FCA1_CRIFA Reviewed; 63 AA.
AC Q23688;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=Putative flagellar calcium-binding protein;
DE Flags: Fragment;
GN Name=CABP;
OS Crithidia fasciculata.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Crithidia.
OX NCBI_TaxID=5656;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=CFC1;
RX PubMed=8943327; DOI=10.1128/mcb.16.12.6724;
RA Pasion S.G., Hines J.C., Ou X., Mahmood R., Ray D.S.;
RT "Sequences within the 5' untranslated region regulate the levels of a
RT kinetoplast DNA topoisomerase mRNA during the cell cycle.";
RL Mol. Cell. Biol. 16:6724-6735(1996).
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the calflagin family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U21305; AAC47410.1; -; mRNA.
DR AlphaFoldDB; Q23688; -.
DR SMR; Q23688; -.
DR VEuPathDB; TriTrypDB:CFAC1_120017200; -.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR InterPro; IPR002048; EF_hand_dom.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 2: Evidence at transcript level;
KW Calcium; Cell projection; Cilium; Flagellum; Metal-binding; Repeat.
FT CHAIN 1..>63
FT /note="Putative flagellar calcium-binding protein"
FT /id="PRO_0000073741"
FT DOMAIN 40..>63
FT /note="EF-hand"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 53
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000305"
FT BINDING 55
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000305"
FT BINDING 57
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000305"
FT BINDING 59
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000305"
FT NON_TER 63
SQ SEQUENCE 63 AA; 7108 MW; 36D414066CD9235D CRC64;
MGCISSKSTQ TGKKEGKTAA ERKAAWEGIR HGLPRRKTAE DKARRIELFK KFDKNNTGKL
SME