FCA_ORYSI
ID FCA_ORYSI Reviewed; 738 AA.
AC B8BCZ8;
DT 05-JUN-2019, integrated into UniProtKB/Swiss-Prot.
DT 05-JUN-2019, sequence version 2.
DT 03-AUG-2022, entry version 71.
DE RecName: Full=Flowering time control protein FCA {ECO:0000305};
DE Short=OsFCA {ECO:0000305};
DE Short=rFCA {ECO:0000303|PubMed:17597396};
GN Name=FCA {ECO:0000305}; ORFNames=OsI_30426 {ECO:0000312|EMBL:EEC84106.1};
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [2]
RP FUNCTION.
RC STRAIN=cv. 9311;
RX PubMed=17597396; DOI=10.1007/s10540-007-9047-y;
RA Hong F., Attia K., Wei C., Li K., He G., Su W., Zhang Q., Qian X., Yang J.;
RT "Overexpression of the rFCA RNA recognition motif affects morphologies
RT modifications in rice (Oryza sativa L.).";
RL Biosci. Rep. 27:225-234(2007).
CC -!- FUNCTION: Plays a major role in the promotion of the transition of the
CC vegetative meristem to reproductive development (By similarity).
CC Required for RNA-mediated chromatin silencing of a range of loci in the
CC genome. Cotranscriptionally recognizes aberrant RNA and marks it for
CC silencing. Controls alternative cleavage and polyadenylation on pre-
CC mRNAs and antisense RNAs (By similarity). Regulates flowering time,
CC seed size and cell volume, probably via the modulation of cell size
CC (PubMed:17597396). {ECO:0000250|UniProtKB:O04425,
CC ECO:0000250|UniProtKB:Q6K271, ECO:0000269|PubMed:17597396}.
CC -!- SUBUNIT: Interacts with FY (By similarity). Binds to SF1, FIK, RPRD1B,
CC OsI_31983 and MADS8 (By similarity). {ECO:0000250|UniProtKB:Q6K271}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q6K271}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EEC84106.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; CM000134; EEC84106.1; ALT_SEQ; Genomic_DNA.
DR AlphaFoldDB; B8BCZ8; -.
DR SMR; B8BCZ8; -.
DR STRING; 39946.B8BCZ8; -.
DR PRIDE; B8BCZ8; -.
DR EnsemblPlants; BGIOSGA030303-TA; BGIOSGA030303-PA; BGIOSGA030303.
DR Gramene; BGIOSGA030303-TA; BGIOSGA030303-PA; BGIOSGA030303.
DR HOGENOM; CLU_020343_0_0_1; -.
DR Proteomes; UP000007015; Chromosome 9.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR GO; GO:0008361; P:regulation of cell size; IMP:UniProtKB.
DR GO; GO:0009909; P:regulation of flower development; IMP:UniProtKB.
DR GO; GO:0080113; P:regulation of seed growth; IMP:UniProtKB.
DR GO; GO:0048510; P:regulation of timing of transition from vegetative to reproductive phase; IEA:EnsemblPlants.
DR CDD; cd00201; WW; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR002343; Hud_Sxl_RNA.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR Pfam; PF00076; RRM_1; 2.
DR Pfam; PF00397; WW; 1.
DR PRINTS; PR00961; HUDSXLRNA.
DR SMART; SM00360; RRM; 2.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF51045; SSF51045; 1.
DR SUPFAM; SSF54928; SSF54928; 2.
DR PROSITE; PS50102; RRM; 2.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 3: Inferred from homology;
KW Developmental protein; Differentiation; Flowering; Nucleus;
KW Reference proteome; Repeat; RNA-binding.
FT CHAIN 1..738
FT /note="Flowering time control protein FCA"
FT /id="PRO_0000447372"
FT DOMAIN 122..203
FT /note="RRM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT DOMAIN 213..293
FT /note="RRM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT DOMAIN 609..642
FT /note="WW"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00224"
FT REGION 1..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 292..451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 566..595
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 670..738
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 345..404
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 430..451
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 738 AA; 79590 MW; E6003090DF6C6B44 CRC64;
MHRGGDRSTD PSSGPAPGSR GGGDGRFGRG PSRWSSGGGG GGSGSPPHRF SRGGGGGGGD
GGGGGGGGGR FHPYRGPSDH SGGGGYRSGG GGEYGEPGSG PRHRYGSGRG DHSDHDNRNN
YVKLFIGSVP RTATEDDVRP LFEEHGDVVE VALIKDRKTG EQQGCCFVKY ATSEEAERAI
RALHNQYTLP GAMGPIQVRY ADGERERHGA IEHKLFVASL NKQATAKEIE EIFAPYGHVE
DVYIMKDGMR QSRGCGFVKF SSREPALAAM SALSGNYVMR GCEQPLIIRF ADPKRPRPGE
SRGGPAFGGP GFSPRSDAAL VIRPTANLDE PRGRHMPPDS WHPSSPRSAP HQFNNFGSDN
PMAPKGSTVT STTDTATFRP QMFSGNGSLS SQTAVPSSSH MGMNPPPMAQ GHHLGGQQIP
PLQKLPGLPQ NFPVQLQNNQ QGQPLQGPAQ QIGQLQVPQS MGPGSFGQNM LSGQLPVSQP
LMQQNASVGA VQAPSAVSNS MQAIPGQQHL PSNVAPQMLQ QPVQQMPSQA PQLLLQQQAA
LQSSYQSSQQ AIYQLQQQLQ LMQQQQQSNL NHQQPTQGQP VQSSNPGAPN AIIPSNINTI
PQQATSPAVP LTCNWTEHTS PEGFKYYYNS ITRESKWDKP EEYVLYEQQQ QQQQQQKLLL
LQQHQQKLAM QQLQSPPQAQ THPAMQPVQQ IPQAQQGQQQ MQMKQQELNY TQLQTPGAID
PSRIQQGIQS AQERAWKS
