FCF1_BOVIN
ID FCF1_BOVIN Reviewed; 198 AA.
AC Q32PD0;
DT 11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=rRNA-processing protein FCF1 homolog;
GN Name=FCF1;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Crossbred X Angus; TISSUE=Liver;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Essential protein involved in pre-rRNA processing and 40S
CC ribosomal subunit assembly. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
CC {ECO:0000305}.
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DR EMBL; BC108165; AAI08166.1; -; mRNA.
DR RefSeq; NP_001032529.1; NM_001037452.1.
DR AlphaFoldDB; Q32PD0; -.
DR SMR; Q32PD0; -.
DR STRING; 9913.ENSBTAP00000027167; -.
DR PaxDb; Q32PD0; -.
DR PRIDE; Q32PD0; -.
DR Ensembl; ENSBTAT00000027167; ENSBTAP00000027167; ENSBTAG00000020381.
DR Ensembl; ENSBTAT00000070689; ENSBTAP00000069268; ENSBTAG00000020381.
DR GeneID; 508270; -.
DR KEGG; bta:508270; -.
DR CTD; 51077; -.
DR VEuPathDB; HostDB:ENSBTAG00000020381; -.
DR VGNC; VGNC:28933; FCF1.
DR eggNOG; KOG3165; Eukaryota.
DR GeneTree; ENSGT00940000153117; -.
DR HOGENOM; CLU_081098_0_1_1; -.
DR InParanoid; Q32PD0; -.
DR OMA; PLITDCV; -.
DR OrthoDB; 1338131at2759; -.
DR TreeFam; TF314992; -.
DR Proteomes; UP000009136; Chromosome 10.
DR Bgee; ENSBTAG00000020381; Expressed in oocyte and 106 other tissues.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR CDD; cd09864; PIN_Fcf1-like; 1.
DR InterPro; IPR006984; Fcf1/Utp23.
DR InterPro; IPR037503; Fcf1_PIN.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR002716; PIN_dom.
DR Pfam; PF04900; Fcf1; 1.
DR SMART; SM00670; PINc; 1.
DR SUPFAM; SSF88723; SSF88723; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT CHAIN 1..198
FT /note="rRNA-processing protein FCF1 homolog"
FT /id="PRO_0000245251"
FT DOMAIN 67..166
FT /note="PINc"
FT REGION 22..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..46
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 198 AA; 23370 MW; A0C98414C21F16AE CRC64;
MGKQKKTRKY ATMKRMLSLR DQRLKEKDRL KPKKKEKKDP SALKEREVPQ HPSCLFFQYN
TQLGPPYHIL VDTNFINFSI KAKLDLVQSM MDCLYAKCIP CITDCVMAEI EKLGQKYRVA
LRIAKDPRFE RLPCTHKGTY ADDCLVQRVT QHKCYIVATV DRDLKRRIRK IPGVPIMYIS
NHRYNIERMP DDYGAPRF