ID   AIM9_YEAST              Reviewed;         627 AA.
AC   P40053; D3DLY7;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 143.
DE   RecName: Full=Altered inheritance of mitochondria protein 9, mitochondrial;
DE   AltName: Full=Found in mitochondrial proteome protein 29;
DE   Flags: Precursor;
GN   Name=AIM9; Synonyms=FMP29; OrderedLocusNames=YER080W;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169868;
RA   Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E.,
RA   Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E.,
RA   Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S.,
RA   Hyman R.W., Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D.,
RA   Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X.,
RA   Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y.,
RA   Botstein D., Davis R.W.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome V.";
RL   Nature 387:78-81(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=14562095; DOI=10.1038/nature02026;
RA   Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA   Weissman J.S., O'Shea E.K.;
RT   "Global analysis of protein localization in budding yeast.";
RL   Nature 425:686-691(2003).
RN   [4]
RP   LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX   PubMed=14562106; DOI=10.1038/nature02046;
RA   Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA   O'Shea E.K., Weissman J.S.;
RT   "Global analysis of protein expression in yeast.";
RL   Nature 425:737-741(2003).
RN   [5]
RP   DISRUPTION PHENOTYPE.
RX   PubMed=19300474; DOI=10.1371/journal.pgen.1000407;
RA   Hess D.C., Myers C.L., Huttenhower C., Hibbs M.A., Hayes A.P., Paw J.,
RA   Clore J.J., Mendoza R.M., Luis B.S., Nislow C., Giaever G., Costanzo M.,
RA   Troyanskaya O.G., Caudy A.A.;
RT   "Computationally driven, quantitative experiments discover genes required
RT   for mitochondrial biogenesis.";
RL   PLoS Genet. 5:E1000407-E1000407(2009).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:14562095}.
CC   -!- DISRUPTION PHENOTYPE: Increases frequency of mitochondrial genome loss.
CC       {ECO:0000269|PubMed:19300474}.
CC   -!- MISCELLANEOUS: Present with 8200 molecules/cell in log phase SD medium.
CC       {ECO:0000269|PubMed:14562106}.
CC   -!- SIMILARITY: Belongs to the AIM9 family. {ECO:0000305}.
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DR   EMBL; U18839; AAB64635.1; -; Genomic_DNA.
DR   EMBL; BK006939; DAA07741.1; -; Genomic_DNA.
DR   PIR; S50583; S50583.
DR   RefSeq; NP_011003.1; NM_001178971.1.
DR   AlphaFoldDB; P40053; -.
DR   BioGRID; 36825; 34.
DR   IntAct; P40053; 1.
DR   STRING; 4932.YER080W; -.
DR   iPTMnet; P40053; -.
DR   MaxQB; P40053; -.
DR   PaxDb; P40053; -.
DR   PRIDE; P40053; -.
DR   EnsemblFungi; YER080W_mRNA; YER080W; YER080W.
DR   GeneID; 856813; -.
DR   KEGG; sce:YER080W; -.
DR   SGD; S000000882; AIM9.
DR   VEuPathDB; FungiDB:YER080W; -.
DR   eggNOG; ENOG502QV1E; Eukaryota.
DR   HOGENOM; CLU_019189_0_1_1; -.
DR   InParanoid; P40053; -.
DR   OMA; HPDLDPM; -.
DR   BioCyc; YEAST:G3O-30251-MON; -.
DR   PRO; PR:P40053; -.
DR   Proteomes; UP000002311; Chromosome V.
DR   RNAct; P40053; protein.
DR   GO; GO:0005739; C:mitochondrion; HDA:SGD.
DR   InterPro; IPR002575; Aminoglycoside_PTrfase.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   Pfam; PF01636; APH; 1.
DR   SUPFAM; SSF56112; SSF56112; 1.
PE   1: Evidence at protein level;
KW   Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..43
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           44..627
FT                   /note="Altered inheritance of mitochondria protein 9,
FT                   mitochondrial"
FT                   /id="PRO_0000202637"
SQ   SEQUENCE   627 AA;  72414 MW;  395479DDEC0F4F51 CRC64;
     MIRYTVAGHS RRCVVGASKR VGAIKCITVA ATKRFISNKP NEVFTKLTND NDPKRDAFFK
     YTWGSWLKND KQEKEKRFTK FSIEGLNRIL NDIYIQSNEM AKAPDGKILP PVFNKNLTVS
     LVNNVVPKNI GKINPNEKVQ VTTLSSIHEG KHHRIYKVDT NLNKAFILRI PYPLENENTL
     SYRIRSEVAT MDFADLKLGI KVPKIFCYGV NSLNPVRQPF VLQEFIEGEL LMKDWDPLIE
     DGSSNQKKYD NVIKQVSDFQ SKLVSLKLNA FGSIYFNNDL KDGNEKEFVK EDIYDGETNP
     DLQNRWKIGP SVERCLWRHK SHLDFHKQMK PFLGPWPKKS PMDIIKNTGL LEAENAKTRI
     AMKEAGSSAE LMYPRTLKEQ ITTYENLAKI APDLFNVKTK AIPNMQELLS PRLFHPDLDP
     MNIIVNKEAQ EAYLLDFEGA CTKPFILQNS PQFIAYDGPK IYDLKEDITD FDKLSEAEKV
     QYQFMYKRTR NQHQWEKKLN DNNPKLITAV APPVKLLRSP YIAAVERKTE EEYLLIDESL
     LQLKEVWDIF AQNELVNQKK FPLNYSKEDI ERHVEDLQKL HEKLISTPFA ATQGWIPQDM
     FDQLLNSGSI VKQENGDYTV KQPEATK