FCT_DICD3
ID FCT_DICD3 Reviewed; 735 AA.
AC Q47162; E0SLE2;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 30-NOV-2010, sequence version 2.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Ferrichrysobactin receptor;
DE Flags: Precursor;
GN Name=fct; OrderedLocusNames=Dda3937_03042;
OS Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Pectobacteriaceae; Dickeya.
OX NCBI_TaxID=198628;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=3937;
RX PubMed=8576065; DOI=10.1128/jb.178.4.1227-1231.1996;
RA Sauvage C., Franza T., Expert D.;
RT "Analysis of the Erwinia chrysanthemi ferrichrysobactin receptor gene:
RT resemblance to the Escherichia coli fepA-fes bidirectional promoter region
RT and homology with hydroxamate receptors.";
RL J. Bacteriol. 178:1227-1231(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3937;
RX PubMed=21217001; DOI=10.1128/jb.01513-10;
RA Glasner J.D., Yang C.H., Reverchon S., Hugouvieux-Cotte-Pattat N.,
RA Condemine G., Bohin J.P., Van Gijsegem F., Yang S., Franza T., Expert D.,
RA Plunkett G. III, San Francisco M.J., Charkowski A.O., Py B., Bell K.,
RA Rauscher L., Rodriguez-Palenzuela P., Toussaint A., Holeva M.C., He S.Y.,
RA Douet V., Boccara M., Blanco C., Toth I., Anderson B.D., Biehl B.S.,
RA Mau B., Flynn S.M., Barras F., Lindeberg M., Birch P.R., Tsuyumu S.,
RA Shi X., Hibbing M., Yap M.N., Carpentier M., Dassa E., Umehara M.,
RA Kim J.F., Rusch M., Soni P., Mayhew G.F., Fouts D.E., Gill S.R.,
RA Blattner F.R., Keen N.T., Perna N.T.;
RT "Genome sequence of the plant-pathogenic bacterium Dickeya dadantii 3937.";
RL J. Bacteriol. 193:2076-2077(2011).
CC -!- FUNCTION: Involved in the initial step of iron uptake by binding
CC chrysobactin, an iron chelatin siderophore that allows the bacteria to
CC extract iron from the environment.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the TonB-dependent receptor family.
CC {ECO:0000305}.
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DR EMBL; X87967; CAA61205.1; -; Genomic_DNA.
DR EMBL; CP002038; ADM99354.1; -; Genomic_DNA.
DR PIR; S57486; S57486.
DR RefSeq; WP_013318789.1; NC_014500.1.
DR AlphaFoldDB; Q47162; -.
DR SMR; Q47162; -.
DR STRING; 198628.Dda3937_03042; -.
DR EnsemblBacteria; ADM99354; ADM99354; Dda3937_03042.
DR GeneID; 9734602; -.
DR KEGG; ddd:Dda3937_03042; -.
DR PATRIC; fig|198628.6.peg.3115; -.
DR eggNOG; COG4774; Bacteria.
DR HOGENOM; CLU_008287_9_0_6; -.
DR OMA; QTGVYFQ; -.
DR OrthoDB; 173242at2; -.
DR BioCyc; DDAD198628:DDA3937_RS14700-MON; -.
DR Proteomes; UP000006859; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015344; F:siderophore uptake transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR Gene3D; 2.170.130.10; -; 1.
DR Gene3D; 2.40.170.20; -; 1.
DR InterPro; IPR012910; Plug_dom.
DR InterPro; IPR037066; Plug_dom_sf.
DR InterPro; IPR039423; TonB-dep_rcpt.
DR InterPro; IPR000531; TonB-dep_rcpt_b-brl.
DR InterPro; IPR010916; TonB_box_CS.
DR InterPro; IPR036942; TonB_rcpt_b-brl_sf.
DR InterPro; IPR010105; TonB_sidphr_rcpt.
DR PANTHER; PTHR32552; PTHR32552; 1.
DR Pfam; PF07715; Plug; 1.
DR Pfam; PF00593; TonB_dep_Rec; 1.
DR TIGRFAMs; TIGR01783; TonB-siderophor; 1.
DR PROSITE; PS00430; TONB_DEPENDENT_REC_1; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Ion transport; Iron; Iron transport; Membrane;
KW Receptor; Reference proteome; Signal; TonB box; Transmembrane;
KW Transmembrane beta strand; Transport.
FT SIGNAL 1..38
FT /evidence="ECO:0000255"
FT CHAIN 39..735
FT /note="Ferrichrysobactin receptor"
FT /id="PRO_0000034745"
FT TOPO_DOM 39..45
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 46..54
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 55..82
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 83..91
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 92..107
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 108..116
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 117..124
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 125..132
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 133..168
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 169..177
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 178
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 179..187
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 188..193
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 194..202
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 203..221
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 222..230
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 231..260
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 261..269
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 270..285
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 286..294
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 295..311
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 312..320
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 321..327
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 328..336
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 337..342
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 343..351
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 352..377
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 378..386
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 387..391
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 392..400
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 401..402
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 403..411
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 412..423
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 424..432
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 433..447
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 448..456
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 457..460
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 461..469
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 470..494
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 495..503
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 504..508
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 509..517
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 518..537
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 538..546
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 547..551
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 552..560
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 561..567
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 568..576
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 577..598
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 599..607
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 608..648
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 649..657
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 658..673
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 674..683
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 684..695
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 696..704
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 705..706
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 707..715
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT TOPO_DOM 716..726
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 727..735
FT /note="Beta stranded"
FT /evidence="ECO:0000255"
FT MOTIF 45..52
FT /note="TonB box"
FT MOTIF 718..735
FT /note="TonB C-terminal box"
FT CONFLICT 91..93
FT /note="RDQ -> ATK (in Ref. 1; CAA61205)"
FT /evidence="ECO:0000305"
FT CONFLICT 104
FT /note="D -> H (in Ref. 1; CAA61205)"
FT /evidence="ECO:0000305"
FT CONFLICT 130..131
FT /note="GF -> PRV (in Ref. 1; CAA61205)"
FT /evidence="ECO:0000305"
FT CONFLICT 495..498
FT /note="GRAG -> RAVR (in Ref. 1; CAA61205)"
FT /evidence="ECO:0000305"
FT CONFLICT 662..681
FT /note="YGDNAESFKVPAYTLFDAMA -> TAITRRASRYRLYPVRRHG (in Ref.
FT 1; CAA61205)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 735 AA; 80724 MW; 7EB830DC14E9CA4F CRC64;
MHSTRNKQLK KLKSWHKNKK AMPAVLASTL LMAAHAQAAE TTGADTMIVS ANAGESVTAP
LKGIVAKESA SGTKTSTPLI KTPQSVTVVT RDQMDAQAVS SVSDALNYSS GVVTNYRGSS
NRNDEVIARG FRYAPKFLDG LSYGLSGQGS TIGKMNPWLL ERVEMVHGPA SVLYGQVNPG
GLISMTSKRP TAETIRKVQF SAGNQHLGEA AFDFGGALND DKTLLYRLDG IASTKHEFVK
DSKQERIAVA PSLTWLPNPD TSFTLLTSYQ NDPKAGYRNF LPKIGTVVEA SAGYIPYDLN
VSDPNYNQSK REQGSIGYNL DHSFNDVFSF QQNVRYTQLR EKYKYLVYTK NADAPATDTT
ILRRPQKEEN EISEFAIDNQ LKATFATGSV NHTVLSGLDY KWLTLEKKMW LDRNNDYSFN
WANPTYNVSV NDSMLTELST NERNKLNQVG VYLQDQLEWN QWNLLLSGRH DWSRVDKQDY
AADTTTERND GKFTGRAGLL YAFDNGISPY VSYSTSFEPN LDSGAPGTPA FKPTTGEQKE
VGVKFQPKGS NTLLTVSLFD ITQKNITSYN SVTRYNEQIG KVKSKGVETE AHTQLTPEIS
LMAAYSYTDA VTKESYTASQ VNKAPSSIPR HAASAWGSYS FHNGPLKGVT LGTGVRYIGS
TYGDNAESFK VPAYTLFDAM ARYELGSLAS QLKGAAVQLN VNNLTDKHYV ASCGGDTACF
YGSGRTVVAT VSYSW
