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FD4L1_ARATH
ID   FD4L1_ARATH             Reviewed;         295 AA.
AC   O04584;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Fatty acid desaturase 4-like 1, chloroplastic;
DE            Short=FAD4-L1;
DE            EC=1.14.19.-;
DE   Flags: Precursor;
GN   Name=FAD4L1; OrderedLocusNames=At1g62190; ORFNames=F19K23.12;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=19682287; DOI=10.1111/j.1365-313x.2009.04001.x;
RA   Gao J., Ajjawi I., Manoli A., Sawin A., Xu C., Froehlich J.E., Last R.L.,
RA   Benning C.;
RT   "FATTY ACID DESATURASE4 of Arabidopsis encodes a protein distinct from
RT   characterized fatty acid desaturases.";
RL   Plant J. 60:832-839(2009).
CC   -!- FUNCTION: Fatty acid desaturase involved in the production of
CC       chloroplast-specific phosphatidylglycerol molecular species. Catalyzes
CC       the formation of a trans double bond introduced close to the carboxyl
CC       group of palmitic acid, which is specifically esterified to the sn-2
CC       glyceryl carbon of phosphatidylglycerol (By similarity). {ECO:0000250}.
CC   -!- PATHWAY: Lipid metabolism; fatty acid metabolism.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the fatty acid desaturase CarF family.
CC       {ECO:0000305}.
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DR   EMBL; AC000375; AAB60765.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE33934.1; -; Genomic_DNA.
DR   PIR; D96648; D96648.
DR   RefSeq; NP_176410.1; NM_104900.3.
DR   AlphaFoldDB; O04584; -.
DR   STRING; 3702.AT1G62190.1; -.
DR   PaxDb; O04584; -.
DR   PRIDE; O04584; -.
DR   ProteomicsDB; 230408; -.
DR   EnsemblPlants; AT1G62190.1; AT1G62190.1; AT1G62190.
DR   GeneID; 842515; -.
DR   Gramene; AT1G62190.1; AT1G62190.1; AT1G62190.
DR   KEGG; ath:AT1G62190; -.
DR   Araport; AT1G62190; -.
DR   TAIR; locus:2018022; AT1G62190.
DR   eggNOG; KOG3011; Eukaryota.
DR   HOGENOM; CLU_065233_0_0_1; -.
DR   InParanoid; O04584; -.
DR   OMA; RQFANNS; -.
DR   PhylomeDB; O04584; -.
DR   UniPathway; UPA00199; -.
DR   PRO; PR:O04584; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR019547; Lipid_desat.
DR   Pfam; PF10520; Lipid_desat; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Fatty acid metabolism; Lipid metabolism; Membrane;
KW   Oxidoreductase; Plastid; Reference proteome; Transit peptide;
KW   Transmembrane; Transmembrane helix.
FT   TRANSIT         1..29
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           30..295
FT                   /note="Fatty acid desaturase 4-like 1, chloroplastic"
FT                   /id="PRO_0000429928"
FT   TRANSMEM        72..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   295 AA;  32954 MW;  489D390FA7EDA680 CRC64;
     MAVSFQTKNP LRPITNIPRS YGPTRVRVTC SVTTTNPQLN HENLVVEKRL VNPPLSKNND
     PTLQSTWTHR LWVAAGSTTI FASFAKSIIG GFGSHLWLQP ALACYAGYVF ADLGSGVYHW
     AIDNYGGAST PIVGAQLEAS QGHHKYPWTI TKRQFANNSY TIARAITFIV LPLNLAINNP
     LFHSFVSTFA FCILLSQQFH AWAHGTKSKL PPLVMALQDM GLLVSRKDHP GHHQAPYNSN
     YCVVSGAWNK VLDESNLFKA LEMALFFQFG VRPNSWNEPN SDWTEETETN FFTKI
 
 
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