ID   FDHC_METFO              Reviewed;         280 AA.
AC   P35839;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Probable formate transporter;
GN   Name=fdhC;
OS   Methanobacterium formicicum.
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanobacterium.
OX   NCBI_TaxID=2162;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=JF-1;
RX   PubMed=1378430; DOI=10.1128/jb.174.15.4997-5004.1992;
RA   White W.B., Ferry J.G.;
RT   "Identification of formate dehydrogenase-specific mRNA species and
RT   nucleotide sequence of the fdhC gene of Methanobacterium formicicum.";
RL   J. Bacteriol. 174:4997-5004(1992).
CC   -!- FUNCTION: May act as a formate transporter.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FNT transporter (TC 2.A.44) family.
CC       {ECO:0000305}.
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DR   EMBL; M64798; AAA73026.1; -; Genomic_DNA.
DR   PIR; A42712; A42712.
DR   AlphaFoldDB; P35839; -.
DR   SMR; P35839; -.
DR   STRING; 2162.BRM9_0169; -.
DR   TCDB; 1.A.16.2.1; the formate-nitrite transporter (fnt) family.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015499; F:formate transmembrane transporter activity; IDA:MENGO.
DR   Gene3D; 1.20.1080.10; -; 1.
DR   InterPro; IPR023271; Aquaporin-like.
DR   InterPro; IPR000292; For/NO2_transpt.
DR   InterPro; IPR024002; For/NO2_transpt_CS.
DR   PANTHER; PTHR30520; PTHR30520; 1.
DR   Pfam; PF01226; Form_Nir_trans; 1.
DR   TIGRFAMs; TIGR00790; fnt; 1.
DR   PROSITE; PS01005; FORMATE_NITRITE_TP_1; 1.
DR   PROSITE; PS01006; FORMATE_NITRITE_TP_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..280
FT                   /note="Probable formate transporter"
FT                   /id="PRO_0000094722"
FT   TRANSMEM        33..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        116..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        177..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        204..219
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        253..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   280 AA;  29437 MW;  8706D209F6FE0099 CRC64;
     MASSFKSPAD TAKACVGVAA LKEKAPLSNL IVLSFVAGAY IAFGGLLAEV ATGGMAAAGW
     PTGLVKLVFG GVFPVGLMLV VIAGSELFTG NCMYMPMGIL QGEASVMGTI KNWVGSWVFN
     LVGALFVAYV LAYLTGILTA EPWAATAVTI AKTKALGGAQ FIAAGKTVTS LSWMQVFWRA
     IGCNWLVCLA VYLAVASDDV IGKSFGIWFP IMAFVCIGFE HVVANMFFIP VGIFIGGVTW
     SQFFINNMIP ATLGNIVGGA IFVGCIYWFT YLRGTNKAKA