ID   FDHC_METTF              Reviewed;         274 AA.
AC   Q50568;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Probable formate transporter;
GN   Name=fdhC;
OS   Methanothermobacter thermautotrophicus (Methanobacterium thermoformicicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=145262;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=DSM 3720 / Z-245;
RX   PubMed=9006048; DOI=10.1128/jb.179.3.899-908.1997;
RA   Noelling J., Reeve J.N.;
RT   "Growth- and substrate-dependent transcription of the formate dehydrogenase
RT   (fdhCAB) operon in Methanobacterium thermoformicicum Z-245.";
RL   J. Bacteriol. 179:899-908(1997).
CC   -!- FUNCTION: May act as a formate transporter.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FNT transporter (TC 2.A.44) family.
CC       {ECO:0000305}.
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DR   EMBL; U52681; AAC44819.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q50568; -.
DR   SMR; Q50568; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1080.10; -; 1.
DR   InterPro; IPR023271; Aquaporin-like.
DR   InterPro; IPR000292; For/NO2_transpt.
DR   InterPro; IPR024002; For/NO2_transpt_CS.
DR   PANTHER; PTHR30520; PTHR30520; 1.
DR   Pfam; PF01226; Form_Nir_trans; 1.
DR   TIGRFAMs; TIGR00790; fnt; 1.
DR   PROSITE; PS01005; FORMATE_NITRITE_TP_1; 1.
DR   PROSITE; PS01006; FORMATE_NITRITE_TP_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..274
FT                   /note="Probable formate transporter"
FT                   /id="PRO_0000094723"
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        118..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        200..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        226..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        248..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   274 AA;  29071 MW;  B0D047347BF7B1A4 CRC64;
     MGSSFKSPAD TAKACSAIAE LKEKAPLGKV IVLSFLAGAY IAFGGLLAEV VTGGMAKAGY
     PAGLVKLVFG AVFPVGLMLV VIAGSELFTG NCMYMPLGIL DKRASIMGLI RNWVTSWVFN
     LVGAVFVAYF LAVATGILTA DPWQAGALTV AKTKALGGAS FIAAGKVTKS LTWAQAFWRA
     VGCNWLVCLA VYLAIASDDI IGKIWGIWFP IFAFVAIGFE HSVANMFFIP VGIFLGGVTW
     SQFFMNNLIP VTLGNIVGGA IFVACLYWYT YLKE