ID   FDHD_ALKCK              Reviewed;         267 AA.
AC   Q5WJL4;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Sulfur carrier protein FdhD {ECO:0000255|HAMAP-Rule:MF_00187};
GN   Name=fdhD {ECO:0000255|HAMAP-Rule:MF_00187}; OrderedLocusNames=ABC0902;
OS   Alkalihalobacillus clausii (strain KSM-K16) (Bacillus clausii).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus.
OX   NCBI_TaxID=66692;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KSM-K16;
RA   Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y.,
RA   Kawai S., Ito S., Horikoshi K.;
RT   "The complete genome sequence of the alkaliphilic Bacillus clausii KSM-
RT   K16.";
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for formate dehydrogenase (FDH) activity. Acts as a
CC       sulfur carrier protein that transfers sulfur from IscS to the
CC       molybdenum cofactor prior to its insertion into FDH.
CC       {ECO:0000255|HAMAP-Rule:MF_00187}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00187}.
CC   -!- SIMILARITY: Belongs to the FdhD family. {ECO:0000255|HAMAP-
CC       Rule:MF_00187}.
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DR   EMBL; AP006627; BAD63441.1; -; Genomic_DNA.
DR   RefSeq; WP_011245757.1; NC_006582.1.
DR   AlphaFoldDB; Q5WJL4; -.
DR   SMR; Q5WJL4; -.
DR   STRING; 66692.ABC0902; -.
DR   EnsemblBacteria; BAD63441; BAD63441; ABC0902.
DR   KEGG; bcl:ABC0902; -.
DR   eggNOG; COG1526; Bacteria.
DR   HOGENOM; CLU_056887_4_1_9; -.
DR   OMA; RAFWNLK; -.
DR   OrthoDB; 948173at2; -.
DR   Proteomes; UP000001168; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0097163; F:sulfur carrier activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016783; F:sulfurtransferase activity; IEA:InterPro.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00187; FdhD; 1.
DR   InterPro; IPR016193; Cytidine_deaminase-like.
DR   InterPro; IPR003786; FdhD.
DR   PANTHER; PTHR30592; PTHR30592; 1.
DR   Pfam; PF02634; FdhD-NarQ; 1.
DR   PIRSF; PIRSF015626; FdhD; 1.
DR   SUPFAM; SSF53927; SSF53927; 1.
DR   TIGRFAMs; TIGR00129; fdhD_narQ; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Molybdenum cofactor biosynthesis; Reference proteome.
FT   CHAIN           1..267
FT                   /note="Sulfur carrier protein FdhD"
FT                   /id="PRO_0000152889"
FT   ACT_SITE        108
FT                   /note="Cysteine persulfide intermediate"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00187"
SQ   SEQUENCE   267 AA;  30043 MW;  6BF6B5A19DF3F799 CRC64;
     MEKNIQTSRQ IWRFQAGEPV RIDDPIAREQ PVTLKINGEE FATLVCTPTY LQEMAIGFLV
     SEGLIQAYEE VKTIWIDDRQ GFIHIELVRP IDRLHQHLQT KRYMGSCCGM SRQGFVFASD
     AKTAKKVQTR DVKLNAGDCF RLMAELQENA RTFQQTGGVH NAALATKDGL LLMREDVGRH
     NALDKLYGHC LQNGLSLHGK LVVFSGRLSA EIILKVAKIG CELVLSKSAP TDRALQIAEE
     LDITTVGFIR NRSMNVYTVP ERIELKS