ID   FDHD_ANADE              Reviewed;         288 AA.
AC   Q2IP67;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Sulfur carrier protein FdhD {ECO:0000255|HAMAP-Rule:MF_00187};
GN   Name=fdhD {ECO:0000255|HAMAP-Rule:MF_00187}; OrderedLocusNames=Adeh_0826;
OS   Anaeromyxobacter dehalogenans (strain 2CP-C).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Anaeromyxobacteraceae; Anaeromyxobacter.
OX   NCBI_TaxID=290397;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2CP-C;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R.,
RA   Gilna P., Kiss H., Schmutz J., Larimer F., Land M., Kyrpides N.,
RA   Anderson I., Sanford R.A., Ritalahti K.M., Thomas H.S., Kirby J.R.,
RA   Zhulin I.B., Loeffler F.E., Richardson P.;
RT   "Complete sequence of Anaeromyxobacter dehalogenans 2CP-C.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for formate dehydrogenase (FDH) activity. Acts as a
CC       sulfur carrier protein that transfers sulfur from IscS to the
CC       molybdenum cofactor prior to its insertion into FDH.
CC       {ECO:0000255|HAMAP-Rule:MF_00187}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00187}.
CC   -!- SIMILARITY: Belongs to the FdhD family. {ECO:0000255|HAMAP-
CC       Rule:MF_00187}.
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DR   EMBL; CP000251; ABC80601.1; -; Genomic_DNA.
DR   RefSeq; WP_011419884.1; NC_007760.1.
DR   AlphaFoldDB; Q2IP67; -.
DR   SMR; Q2IP67; -.
DR   STRING; 290397.Adeh_0826; -.
DR   EnsemblBacteria; ABC80601; ABC80601; Adeh_0826.
DR   KEGG; ade:Adeh_0826; -.
DR   eggNOG; COG1526; Bacteria.
DR   HOGENOM; CLU_056887_3_0_7; -.
DR   OMA; RAFWNLK; -.
DR   Proteomes; UP000001935; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0097163; F:sulfur carrier activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016783; F:sulfurtransferase activity; IEA:InterPro.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00187; FdhD; 1.
DR   InterPro; IPR016193; Cytidine_deaminase-like.
DR   InterPro; IPR003786; FdhD.
DR   PANTHER; PTHR30592; PTHR30592; 1.
DR   Pfam; PF02634; FdhD-NarQ; 1.
DR   PIRSF; PIRSF015626; FdhD; 1.
DR   SUPFAM; SSF53927; SSF53927; 1.
DR   TIGRFAMs; TIGR00129; fdhD_narQ; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Molybdenum cofactor biosynthesis; Reference proteome.
FT   CHAIN           1..288
FT                   /note="Sulfur carrier protein FdhD"
FT                   /id="PRO_1000098777"
FT   ACT_SITE        122
FT                   /note="Cysteine persulfide intermediate"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00187"
FT   BINDING         268..273
FT                   /ligand="Mo-bis(molybdopterin guanine dinucleotide)"
FT                   /ligand_id="ChEBI:CHEBI:60539"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00187"
SQ   SEQUENCE   288 AA;  29304 MW;  12C0C44B06BEF68C CRC64;
     METSLKRAAA PAGAVAERTV LRNGGAVRDA LAVEEPLEIR VDGERLATTM RTPGADGDLA
     LGFLFAEGII AGVEDVGTVI HCGRPGEEGY GNVMDVRSAA GMRIDPERVL EGRRFIPVSA
     ACGVCGRLSI DHLMERLRPL PAGEPVPTAL VAAGMETLAR SQPVFERTGG LHAAVLVGRD
     GAPVASAEDV GRHNAVDKVV GAALRAGRVG PRAAAASAPA LLAVSGRAGF EIVQKAAAAG
     VPVVASVSAP SSLAVDLARA AGVTLCGFVR GERMNVYANG ERLGLTGP