FDHD_BACP2
ID FDHD_BACP2 Reviewed; 262 AA.
AC A8FIA1;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 13-NOV-2007, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Sulfur carrier protein FdhD {ECO:0000255|HAMAP-Rule:MF_00187};
GN Name=fdhD {ECO:0000255|HAMAP-Rule:MF_00187}; OrderedLocusNames=BPUM_3315;
OS Bacillus pumilus (strain SAFR-032).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=315750;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAFR-032;
RX PubMed=17895969; DOI=10.1371/journal.pone.0000928;
RA Gioia J., Yerrapragada S., Qin X., Jiang H., Igboeli O.C., Muzny D.,
RA Dugan-Rocha S., Ding Y., Hawes A., Liu W., Perez L., Kovar C., Dinh H.,
RA Lee S., Nazareth L., Blyth P., Holder M., Buhay C., Tirumalai M.R., Liu Y.,
RA Dasgupta I., Bokhetache L., Fujita M., Karouia F., Eswara Moorthy P.,
RA Siefert J., Uzman A., Buzumbo P., Verma A., Zwiya H., McWilliams B.D.,
RA Olowu A., Clinkenbeard K.D., Newcombe D., Golebiewski L., Petrosino J.F.,
RA Nicholson W.L., Fox G.E., Venkateswaran K., Highlander S.K.,
RA Weinstock G.M.;
RT "Paradoxical DNA repair and peroxide resistance gene conservation in
RT Bacillus pumilus SAFR-032.";
RL PLoS ONE 2:E928-E928(2007).
CC -!- FUNCTION: Required for formate dehydrogenase (FDH) activity. Acts as a
CC sulfur carrier protein that transfers sulfur from IscS to the
CC molybdenum cofactor prior to its insertion into FDH.
CC {ECO:0000255|HAMAP-Rule:MF_00187}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00187}.
CC -!- SIMILARITY: Belongs to the FdhD family. {ECO:0000255|HAMAP-
CC Rule:MF_00187}.
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DR EMBL; CP000813; ABV63968.1; -; Genomic_DNA.
DR RefSeq; WP_012011536.1; NZ_VEIS01000002.1.
DR AlphaFoldDB; A8FIA1; -.
DR SMR; A8FIA1; -.
DR STRING; 315750.BPUM_3315; -.
DR EnsemblBacteria; ABV63968; ABV63968; BPUM_3315.
DR KEGG; bpu:BPUM_3315; -.
DR eggNOG; COG1526; Bacteria.
DR HOGENOM; CLU_056887_4_1_9; -.
DR OMA; RYCAGAT; -.
DR OrthoDB; 948173at2; -.
DR Proteomes; UP000001355; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0097163; F:sulfur carrier activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016783; F:sulfurtransferase activity; IEA:InterPro.
DR GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00187; FdhD; 1.
DR InterPro; IPR016193; Cytidine_deaminase-like.
DR InterPro; IPR003786; FdhD.
DR PANTHER; PTHR30592; PTHR30592; 1.
DR Pfam; PF02634; FdhD-NarQ; 1.
DR PIRSF; PIRSF015626; FdhD; 1.
DR SUPFAM; SSF53927; SSF53927; 1.
DR TIGRFAMs; TIGR00129; fdhD_narQ; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Molybdenum cofactor biosynthesis; Reference proteome.
FT CHAIN 1..262
FT /note="Sulfur carrier protein FdhD"
FT /id="PRO_1000058458"
FT ACT_SITE 107
FT /note="Cysteine persulfide intermediate"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00187"
SQ SEQUENCE 262 AA; 29583 MW; 9B0428BA3AFC0C17 CRC64;
MNPSVKKKRV IHQYREGQFT CKTDEVVEEF PLTVIVNGEE FVTLVCSPDH LKELVIGFLA
SEGVIRFENE IKRFTIDESM GFAYVDLVHS SEFQSSDFTK RVIGSCCGKG RHFYFLQDVK
TAKTAIDRIN ISADTCMRLM KSLQEESQLF QHTGGVHNAG LCDTEKLFIT RTDIGRHNAL
DKIYGYCLLH QIPLRDKILV FSGRISSEVL LKAAKLGVSI VISKSAPTEL ALNMAEELNI
TTVGFVRGES FNIYTHHQRI TE