FDHD_BACSU
ID FDHD_BACSU Reviewed; 262 AA.
AC P39756;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Sulfur carrier protein FdhD {ECO:0000255|HAMAP-Rule:MF_00187};
GN Name=fdhD {ECO:0000255|HAMAP-Rule:MF_00187};
GN Synonyms=narAA, narQ {ECO:0000303|PubMed:7860592};
GN OrderedLocusNames=BSU36710;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC STRAIN=168;
RX PubMed=7860592; DOI=10.1128/jb.177.4.1112-1115.1995;
RA Glaser P., Danchin A., Kunst F., Zuber P., Nakano M.M.;
RT "Identification and isolation of a gene required for nitrate assimilation
RT and anaerobic growth of Bacillus subtilis.";
RL J. Bacteriol. 177:1112-1115(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RA Glaser P., Danchin A., Kunst F., Moszer I.;
RL Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
CC -!- FUNCTION: Required for formate dehydrogenase (FDH) activity
CC (PubMed:7860592). Acts as a sulfur carrier protein that transfers
CC sulfur from IscS to the molybdenum cofactor prior to its insertion into
CC FDH (By similarity). {ECO:0000255|HAMAP-Rule:MF_00187,
CC ECO:0000269|PubMed:7860592}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00187}.
CC -!- SIMILARITY: Belongs to the FdhD family. {ECO:0000255|HAMAP-
CC Rule:MF_00187}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; Z35277; CAA84539.1; -; Genomic_DNA.
DR EMBL; Z81356; CAB03682.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB15688.1; -; Genomic_DNA.
DR PIR; B69665; B69665.
DR RefSeq; NP_391552.1; NC_000964.3.
DR RefSeq; WP_003227709.1; NZ_JNCM01000034.1.
DR AlphaFoldDB; P39756; -.
DR SMR; P39756; -.
DR STRING; 224308.BSU36710; -.
DR PaxDb; P39756; -.
DR PRIDE; P39756; -.
DR EnsemblBacteria; CAB15688; CAB15688; BSU_36710.
DR GeneID; 936976; -.
DR KEGG; bsu:BSU36710; -.
DR PATRIC; fig|224308.179.peg.3974; -.
DR eggNOG; COG1526; Bacteria.
DR InParanoid; P39756; -.
DR OMA; RYCAGAT; -.
DR PhylomeDB; P39756; -.
DR BioCyc; BSUB:BSU36710-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0097163; F:sulfur carrier activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016783; F:sulfurtransferase activity; IEA:InterPro.
DR GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00187; FdhD; 1.
DR InterPro; IPR016193; Cytidine_deaminase-like.
DR InterPro; IPR003786; FdhD.
DR PANTHER; PTHR30592; PTHR30592; 1.
DR Pfam; PF02634; FdhD-NarQ; 1.
DR PIRSF; PIRSF015626; FdhD; 1.
DR SUPFAM; SSF53927; SSF53927; 1.
DR TIGRFAMs; TIGR00129; fdhD_narQ; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Molybdenum cofactor biosynthesis; Reference proteome.
FT CHAIN 1..262
FT /note="Sulfur carrier protein FdhD"
FT /id="PRO_0000152890"
FT ACT_SITE 107
FT /note="Cysteine persulfide intermediate"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00187"
SQ SEQUENCE 262 AA; 29290 MW; B3CBEE742A7D6CAA CRC64;
MNDKVTAVRD VWRYEQGEIS KVEDRMVTEF PLTVILNGSE FVTLVCTPEH IEELVIGFLA
SEGVIRFQKE IKRFTIDESL GFVYVDLVHP ETLDQKDYTK RVIGSCCGKG RHFYFQQDVK
TAKTAVSQIK ISPEACLALM KDMQQGSGTF QDTGGVHNAA LCDTEKLLLM RTDIGRHNAL
DKLYGHCLLN GMSVRDKLIV FSGRISSEVL LKAAKIGVSI VISKSAPTEL AIQMAEELNI
TAIGFVRNGS FNVYTHPERI RE
