ID   FDHD_BRUAB              Reviewed;         269 AA.
AC   Q578I2;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Sulfur carrier protein FdhD {ECO:0000255|HAMAP-Rule:MF_00187};
GN   Name=fdhD {ECO:0000255|HAMAP-Rule:MF_00187}; OrderedLocusNames=BruAb2_0534;
OS   Brucella abortus biovar 1 (strain 9-941).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=262698;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=9-941;
RX   PubMed=15805518; DOI=10.1128/jb.187.8.2715-2726.2005;
RA   Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z.,
RA   Li L.-L., Kapur V., Alt D.P., Olsen S.C.;
RT   "Completion of the genome sequence of Brucella abortus and comparison to
RT   the highly similar genomes of Brucella melitensis and Brucella suis.";
RL   J. Bacteriol. 187:2715-2726(2005).
CC   -!- FUNCTION: Required for formate dehydrogenase (FDH) activity. Acts as a
CC       sulfur carrier protein that transfers sulfur from IscS to the
CC       molybdenum cofactor prior to its insertion into FDH.
CC       {ECO:0000255|HAMAP-Rule:MF_00187}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00187}.
CC   -!- SIMILARITY: Belongs to the FdhD family. {ECO:0000255|HAMAP-
CC       Rule:MF_00187}.
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DR   EMBL; AE017224; AAX75952.1; -; Genomic_DNA.
DR   RefSeq; WP_002965945.1; NC_006933.1.
DR   AlphaFoldDB; Q578I2; -.
DR   SMR; Q578I2; -.
DR   EnsemblBacteria; AAX75952; AAX75952; BruAb2_0534.
DR   GeneID; 3827285; -.
DR   KEGG; bmb:BruAb2_0534; -.
DR   HOGENOM; CLU_056887_2_1_5; -.
DR   OMA; RYCAGAT; -.
DR   Proteomes; UP000000540; Chromosome II.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0097163; F:sulfur carrier activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016783; F:sulfurtransferase activity; IEA:InterPro.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00187; FdhD; 1.
DR   InterPro; IPR016193; Cytidine_deaminase-like.
DR   InterPro; IPR003786; FdhD.
DR   PANTHER; PTHR30592; PTHR30592; 1.
DR   Pfam; PF02634; FdhD-NarQ; 1.
DR   PIRSF; PIRSF015626; FdhD; 1.
DR   SUPFAM; SSF53927; SSF53927; 1.
DR   TIGRFAMs; TIGR00129; fdhD_narQ; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Molybdenum cofactor biosynthesis.
FT   CHAIN           1..269
FT                   /note="Sulfur carrier protein FdhD"
FT                   /id="PRO_0000152893"
FT   ACT_SITE        111
FT                   /note="Cysteine persulfide intermediate"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00187"
SQ   SEQUENCE   269 AA;  28875 MW;  CF9491E3415F2A98 CRC64;
     MTNQKISRDV HHLAHRMSGF QESSRIVPEE APIAMSYNGT TQAVMMATPG DLEDFAIGFS
     LTENIVTRIE EIEALDIVAF ESGIDIQMKL AKQPEQRLSA RRRFMAGPVG CGLCGIDSIE
     QALRPLHPLE ECSTTFTTRD IAAAVASLGA AQALNAKTHA THGAGFFRPG EGLFAVREDI
     GRHNALDKLI GAVAREGLLA EEGIVAITSR VSVEMVQKAV MLGVPVLAAI SAPTALAIRT
     AEAANLTLVA LVRDEEFDIY THCGRIIES