ID   FDHD_GEOKA              Reviewed;         263 AA.
AC   Q5L2T4;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Sulfur carrier protein FdhD {ECO:0000255|HAMAP-Rule:MF_00187};
GN   Name=fdhD {ECO:0000255|HAMAP-Rule:MF_00187}; OrderedLocusNames=GK0461;
OS   Geobacillus kaustophilus (strain HTA426).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus;
OC   Geobacillus thermoleovorans group.
OX   NCBI_TaxID=235909;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTA426;
RX   PubMed=15576355; DOI=10.1093/nar/gkh970;
RA   Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H.,
RA   Matsui S., Uchiyama I.;
RT   "Thermoadaptation trait revealed by the genome sequence of thermophilic
RT   Geobacillus kaustophilus.";
RL   Nucleic Acids Res. 32:6292-6303(2004).
CC   -!- FUNCTION: Required for formate dehydrogenase (FDH) activity. Acts as a
CC       sulfur carrier protein that transfers sulfur from IscS to the
CC       molybdenum cofactor prior to its insertion into FDH.
CC       {ECO:0000255|HAMAP-Rule:MF_00187}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00187}.
CC   -!- SIMILARITY: Belongs to the FdhD family. {ECO:0000255|HAMAP-
CC       Rule:MF_00187}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000043; BAD74746.1; -; Genomic_DNA.
DR   RefSeq; WP_011229965.1; NC_006510.1.
DR   AlphaFoldDB; Q5L2T4; -.
DR   SMR; Q5L2T4; -.
DR   STRING; 235909.GK0461; -.
DR   EnsemblBacteria; BAD74746; BAD74746; GK0461.
DR   KEGG; gka:GK0461; -.
DR   eggNOG; COG1526; Bacteria.
DR   HOGENOM; CLU_056887_4_1_9; -.
DR   OMA; RYCAGAT; -.
DR   Proteomes; UP000001172; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0097163; F:sulfur carrier activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016783; F:sulfurtransferase activity; IEA:InterPro.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00187; FdhD; 1.
DR   InterPro; IPR016193; Cytidine_deaminase-like.
DR   InterPro; IPR003786; FdhD.
DR   PANTHER; PTHR30592; PTHR30592; 1.
DR   Pfam; PF02634; FdhD-NarQ; 1.
DR   PIRSF; PIRSF015626; FdhD; 1.
DR   SUPFAM; SSF53927; SSF53927; 1.
DR   TIGRFAMs; TIGR00129; fdhD_narQ; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Molybdenum cofactor biosynthesis; Reference proteome.
FT   CHAIN           1..263
FT                   /note="Sulfur carrier protein FdhD"
FT                   /id="PRO_0000152903"
FT   ACT_SITE        107
FT                   /note="Cysteine persulfide intermediate"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00187"
SQ   SEQUENCE   263 AA;  28668 MW;  E3A52D511526A628 CRC64;
     MSGFAAKRRP IAKYRNGRFV EEEDEIALEF PLTITVNGEE FATIVCTPAH LDELVIGFLA
     SEGAIRTCSD IKGMTIDGER GFAYVELAAG GLPAKQFYAK RFIGSCCGKS RQFYFYNDMK
     TAKTIVGGIT VKADDCIRLM KALHERSTDF AATGGLHNAA LATPDEMVVI RSDIGRHNAL
     DKLYGYCLRH QVAMKDKLIV FSGRVSSEVL LKAAKMGVSV LLSKSAPTTL ALDLADELGI
     TVVGFLRGQA FNVYTHESRI IIG