ID   FDHD_LISMO              Reviewed;         261 AA.
AC   Q8Y471;
DT   30-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Sulfur carrier protein FdhD {ECO:0000255|HAMAP-Rule:MF_00187};
GN   Name=fdhD {ECO:0000255|HAMAP-Rule:MF_00187}; OrderedLocusNames=lmo2584;
OS   Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=169963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-679 / EGD-e;
RX   PubMed=11679669; DOI=10.1126/science.1063447;
RA   Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA   Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA   Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA   Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.-D.,
RA   Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W.,
RA   Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U.,
RA   Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A.,
RA   Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B.,
RA   Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N.,
RA   Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT   "Comparative genomics of Listeria species.";
RL   Science 294:849-852(2001).
CC   -!- FUNCTION: Required for formate dehydrogenase (FDH) activity. Acts as a
CC       sulfur carrier protein that transfers sulfur from IscS to the
CC       molybdenum cofactor prior to its insertion into FDH.
CC       {ECO:0000255|HAMAP-Rule:MF_00187}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00187}.
CC   -!- SIMILARITY: Belongs to the FdhD family. {ECO:0000255|HAMAP-
CC       Rule:MF_00187}.
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DR   EMBL; AL591983; CAD00662.1; -; Genomic_DNA.
DR   PIR; AH1397; AH1397.
DR   RefSeq; NP_466107.1; NC_003210.1.
DR   RefSeq; WP_010990022.1; NZ_CP023861.1.
DR   AlphaFoldDB; Q8Y471; -.
DR   SMR; Q8Y471; -.
DR   STRING; 169963.lmo2584; -.
DR   PaxDb; Q8Y471; -.
DR   EnsemblBacteria; CAD00662; CAD00662; CAD00662.
DR   GeneID; 987234; -.
DR   KEGG; lmo:lmo2584; -.
DR   PATRIC; fig|169963.11.peg.2648; -.
DR   eggNOG; COG1526; Bacteria.
DR   HOGENOM; CLU_056887_4_1_9; -.
DR   OMA; RAFWNLK; -.
DR   PhylomeDB; Q8Y471; -.
DR   BioCyc; LMON169963:LMO2584-MON; -.
DR   Proteomes; UP000000817; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0097163; F:sulfur carrier activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016783; F:sulfurtransferase activity; IEA:InterPro.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00187; FdhD; 1.
DR   InterPro; IPR016193; Cytidine_deaminase-like.
DR   InterPro; IPR003786; FdhD.
DR   PANTHER; PTHR30592; PTHR30592; 1.
DR   Pfam; PF02634; FdhD-NarQ; 1.
DR   PIRSF; PIRSF015626; FdhD; 1.
DR   SUPFAM; SSF53927; SSF53927; 1.
DR   TIGRFAMs; TIGR00129; fdhD_narQ; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Molybdenum cofactor biosynthesis; Reference proteome.
FT   CHAIN           1..261
FT                   /note="Sulfur carrier protein FdhD"
FT                   /id="PRO_0000152908"
FT   ACT_SITE        105
FT                   /note="Cysteine persulfide intermediate"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00187"
FT   BINDING         245..250
FT                   /ligand="Mo-bis(molybdopterin guanine dinucleotide)"
FT                   /ligand_id="ChEBI:CHEBI:60539"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00187"
SQ   SEQUENCE   261 AA;  29046 MW;  F8516F3DCCB6A1C6 CRC64;
     MDIVSHQKIR RFEAGTFQEI ESSVATEYPL TIYVNDQELV TIVCTPEYLE DLVVGFLTSE
     GIVRGPRDIN SVDIIEATGH AKVSANFVNK FNAKYRGKRY ITSCCGKSRE NFYFQSDASL
     VNVKQNGNLQ LTTDMIFRLM EKFEQNSATF HQTGGVHNAA LCSSAEIIYS RMDIGRHNAL
     DKIYGRALQD GTSTEDKAII FSGRISSEIL VKTAKLGCGI ILSRSAPTEL AINMAEELNI
     TTVGFIRGDR LNVYSGFERI T