ID   FDHD_STAHJ              Reviewed;         264 AA.
AC   Q4L8E4;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Sulfur carrier protein FdhD {ECO:0000255|HAMAP-Rule:MF_00187};
GN   Name=fdhD {ECO:0000255|HAMAP-Rule:MF_00187}; OrderedLocusNames=SH0772;
OS   Staphylococcus haemolyticus (strain JCSC1435).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=279808;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCSC1435;
RX   PubMed=16237012; DOI=10.1128/jb.187.21.7292-7308.2005;
RA   Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y.,
RA   Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C.,
RA   Hiramatsu K.;
RT   "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the
RT   extreme plasticity of its genome and the evolution of human-colonizing
RT   staphylococcal species.";
RL   J. Bacteriol. 187:7292-7308(2005).
CC   -!- FUNCTION: Required for formate dehydrogenase (FDH) activity. Acts as a
CC       sulfur carrier protein that transfers sulfur from IscS to the
CC       molybdenum cofactor prior to its insertion into FDH.
CC       {ECO:0000255|HAMAP-Rule:MF_00187}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00187}.
CC   -!- SIMILARITY: Belongs to the FdhD family. {ECO:0000255|HAMAP-
CC       Rule:MF_00187}.
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DR   EMBL; AP006716; BAE04081.1; -; Genomic_DNA.
DR   RefSeq; WP_011275095.1; NC_007168.1.
DR   AlphaFoldDB; Q4L8E4; -.
DR   SMR; Q4L8E4; -.
DR   STRING; 279808.SH0772; -.
DR   EnsemblBacteria; BAE04081; BAE04081; SH0772.
DR   GeneID; 58063043; -.
DR   KEGG; sha:SH0772; -.
DR   eggNOG; COG1526; Bacteria.
DR   HOGENOM; CLU_056887_4_1_9; -.
DR   OMA; RYCAGAT; -.
DR   OrthoDB; 948173at2; -.
DR   Proteomes; UP000000543; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0097163; F:sulfur carrier activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016783; F:sulfurtransferase activity; IEA:InterPro.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00187; FdhD; 1.
DR   InterPro; IPR016193; Cytidine_deaminase-like.
DR   InterPro; IPR003786; FdhD.
DR   PANTHER; PTHR30592; PTHR30592; 1.
DR   Pfam; PF02634; FdhD-NarQ; 1.
DR   PIRSF; PIRSF015626; FdhD; 1.
DR   SUPFAM; SSF53927; SSF53927; 1.
DR   TIGRFAMs; TIGR00129; fdhD_narQ; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Molybdenum cofactor biosynthesis.
FT   CHAIN           1..264
FT                   /note="Sulfur carrier protein FdhD"
FT                   /id="PRO_1000020826"
FT   ACT_SITE        107
FT                   /note="Cysteine persulfide intermediate"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00187"
SQ   SEQUENCE   264 AA;  29294 MW;  A239B4F333E56A77 CRC64;
     MNKDVLQGQS IIRYEEGQLI QTTDSYVTEF PLTINVNGTE FATVICSPTH MEELVVGFLA
     SEGAIYKKEE IKSLQIDDSK GFAHVELTKD LGDRFEYSTK RMIASCCGKS REFYFHNDAA
     IAKTSMSKIT LTPKQVLNMM TGLQTASTLF KQTGGLHNAA ISDGDEFFEH RQDIGRHNAL
     DKLYGFCLER RIPVRNKVLI FSGRISSEIL LKAAKIGVGV ILSKSAPTTL AITLANDLNI
     TAIGFIRDGS FNIYSHPERI KATE