ID   FDHD_SULAC              Reviewed;         253 AA.
AC   Q4JBU5;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Sulfur carrier protein FdhD {ECO:0000255|HAMAP-Rule:MF_00187};
GN   Name=fdhD {ECO:0000255|HAMAP-Rule:MF_00187}; OrderedLocusNames=Saci_0318;
OS   Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC
OS   15157 / NCIMB 11770).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=330779;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770;
RX   PubMed=15995215; DOI=10.1128/jb.187.14.4992-4999.2005;
RA   Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E.,
RA   Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A.;
RT   "The genome of Sulfolobus acidocaldarius, a model organism of the
RT   Crenarchaeota.";
RL   J. Bacteriol. 187:4992-4999(2005).
CC   -!- FUNCTION: Required for formate dehydrogenase (FDH) activity. Acts as a
CC       sulfur carrier protein that transfers sulfur from IscS to the
CC       molybdenum cofactor prior to its insertion into FDH.
CC       {ECO:0000255|HAMAP-Rule:MF_00187}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00187}.
CC   -!- SIMILARITY: Belongs to the FdhD family. {ECO:0000255|HAMAP-
CC       Rule:MF_00187}.
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DR   EMBL; CP000077; AAY79734.1; -; Genomic_DNA.
DR   RefSeq; WP_011277236.1; NC_007181.1.
DR   AlphaFoldDB; Q4JBU5; -.
DR   SMR; Q4JBU5; -.
DR   STRING; 330779.Saci_0318; -.
DR   EnsemblBacteria; AAY79734; AAY79734; Saci_0318.
DR   GeneID; 3474762; -.
DR   KEGG; sai:Saci_0318; -.
DR   PATRIC; fig|330779.12.peg.314; -.
DR   eggNOG; arCOG04358; Archaea.
DR   HOGENOM; CLU_056887_3_0_2; -.
DR   OMA; RYCAGAT; -.
DR   Proteomes; UP000001018; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0097163; F:sulfur carrier activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016783; F:sulfurtransferase activity; IEA:InterPro.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00187; FdhD; 1.
DR   InterPro; IPR016193; Cytidine_deaminase-like.
DR   InterPro; IPR003786; FdhD.
DR   PANTHER; PTHR30592; PTHR30592; 1.
DR   Pfam; PF02634; FdhD-NarQ; 1.
DR   PIRSF; PIRSF015626; FdhD; 1.
DR   SUPFAM; SSF53927; SSF53927; 1.
DR   TIGRFAMs; TIGR00129; fdhD_narQ; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Molybdenum cofactor biosynthesis; Reference proteome.
FT   CHAIN           1..253
FT                   /note="Sulfur carrier protein FdhD"
FT                   /id="PRO_0000152939"
FT   ACT_SITE        100
FT                   /note="Cysteine persulfide intermediate"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00187"
SQ   SEQUENCE   253 AA;  27856 MW;  A6B1FCA56AC5D134 CRC64;
     MQIRKVKISK VKDGYRASSE DFVAVEEPLQ IFVNEKNLAI IMRTPGNDLE LTLGFLYYED
     YINSLRDVEE ISMLSDNEIH VRLTNGKFVE TRNFVINSSC GICGRGFLNA IELLKSDAKT
     SNEVIISLPE KLRSNQGVFN ITGGLHAAAL FTLSGELISI YEDVGRHNAV DKIIGSLIHK
     RRLPFTEGIL QVSGRIGYEI VSKAIKAGIP IISGISAPTS KAIEIAEDAG ATLVGFVRGN
     SFNVYTHPER IDL