ID   FDHE_AQUAE              Reviewed;         283 AA.
AC   O67150;
DT   10-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Protein FdhE homolog {ECO:0000255|HAMAP-Rule:MF_00611};
GN   Name=fdhE {ECO:0000255|HAMAP-Rule:MF_00611}; OrderedLocusNames=aq_1051;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
CC   -!- FUNCTION: Necessary for formate dehydrogenase activity.
CC       {ECO:0000255|HAMAP-Rule:MF_00611}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00611}.
CC   -!- SIMILARITY: Belongs to the FdhE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00611}.
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DR   EMBL; AE000657; AAC07106.1; -; Genomic_DNA.
DR   PIR; C70390; C70390.
DR   RefSeq; NP_213713.1; NC_000918.1.
DR   RefSeq; WP_010880651.1; NC_000918.1.
DR   AlphaFoldDB; O67150; -.
DR   SMR; O67150; -.
DR   STRING; 224324.aq_1051; -.
DR   EnsemblBacteria; AAC07106; AAC07106; aq_1051.
DR   KEGG; aae:aq_1051; -.
DR   eggNOG; COG3058; Bacteria.
DR   HOGENOM; CLU_071015_1_0_0; -.
DR   InParanoid; O67150; -.
DR   OMA; PVCGFKP; -.
DR   OrthoDB; 876348at2; -.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0008199; F:ferric iron binding; IBA:GO_Central.
DR   GO; GO:0051604; P:protein maturation; IBA:GO_Central.
DR   CDD; cd16341; FdhE; 1.
DR   Gene3D; 3.90.1670.10; -; 1.
DR   HAMAP; MF_00611; FdeH; 1.
DR   InterPro; IPR024064; FdhE-like_sf.
DR   InterPro; IPR006452; Formate_DH_accessory.
DR   PANTHER; PTHR37689; PTHR37689; 1.
DR   Pfam; PF04216; FdhE; 1.
DR   PIRSF; PIRSF018296; Format_dh_formtn; 1.
DR   SUPFAM; SSF144020; SSF144020; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..283
FT                   /note="Protein FdhE homolog"
FT                   /id="PRO_0000189637"
SQ   SEQUENCE   283 AA;  33169 MW;  BDE886714EAC96B1 CRC64;
     MWGGEMNIFK QKEREFALNR IPVLKEKFPE SNQILNFLSH ILEYHNSIIS EISDLSISLD
     NQNIESRLGK GKPALKLSEY DFEPFLKYFY PLLNIVYEHG TPQMKERVEH LQSLEKKEIL
     SLISSFLENG ISDDMLRFFL ISYLQPILYT FADKVKFEHE RWFKNYCPVC GSKPSVSFIM
     DTEDWEGARF LRCSVCLTDW LYVRTKCVNC GNVEDDSLDY FISSELDYIE IQTCKKCNSY
     IKIIDLRKDG LAVPDLEDIA SVSLDLWAQE QGFIKVERNF MGY