ID   FDHE_ECOBW              Reviewed;         309 AA.
AC   C5A059;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Protein FdhE {ECO:0000255|HAMAP-Rule:MF_00611};
GN   Name=fdhE {ECO:0000255|HAMAP-Rule:MF_00611}; OrderedLocusNames=BWG_3561;
OS   Escherichia coli (strain K12 / MC4100 / BW2952).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=595496;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MC4100 / BW2952;
RX   PubMed=19376874; DOI=10.1128/jb.00118-09;
RA   Ferenci T., Zhou Z., Betteridge T., Ren Y., Liu Y., Feng L., Reeves P.R.,
RA   Wang L.;
RT   "Genomic sequencing reveals regulatory mutations and recombinational events
RT   in the widely used MC4100 lineage of Escherichia coli K-12.";
RL   J. Bacteriol. 191:4025-4029(2009).
CC   -!- FUNCTION: Necessary for formate dehydrogenase activity.
CC       {ECO:0000255|HAMAP-Rule:MF_00611}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00611}.
CC   -!- SIMILARITY: Belongs to the FdhE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00611}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP001396; ACR63124.1; -; Genomic_DNA.
DR   RefSeq; WP_000027703.1; NC_012759.1.
DR   AlphaFoldDB; C5A059; -.
DR   SMR; C5A059; -.
DR   KEGG; ebw:BWG_3561; -.
DR   HOGENOM; CLU_055275_0_0_6; -.
DR   OMA; PKNLYQR; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   CDD; cd16341; FdhE; 1.
DR   Gene3D; 3.90.1670.10; -; 1.
DR   HAMAP; MF_00611; FdeH; 1.
DR   InterPro; IPR024064; FdhE-like_sf.
DR   InterPro; IPR006452; Formate_DH_accessory.
DR   PANTHER; PTHR37689; PTHR37689; 1.
DR   Pfam; PF04216; FdhE; 1.
DR   PIRSF; PIRSF018296; Format_dh_formtn; 1.
DR   SUPFAM; SSF144020; SSF144020; 1.
DR   TIGRFAMs; TIGR01562; FdhE; 1.
PE   3: Inferred from homology;
KW   Cytoplasm.
FT   CHAIN           1..309
FT                   /note="Protein FdhE"
FT                   /id="PRO_1000212265"
SQ   SEQUENCE   309 AA;  34747 MW;  F9A0B30CC980D6E6 CRC64;
     MSIRIIPQDE LGSSEKRTAD MIPPLLFPRL KNLYNRRAER LRELAENNPL GDYLRFAALI
     AHAQEVVLYD HPLEMDLTAR IKEASAQGKP PLDIHVLPRD KHWQKLLMAL IAELKPEMSG
     PALAVIENLE KASTQELEDM ASALFASDFS SVSSDKAPFI WAALSLYWAQ MANLIPGKAR
     AEYGEQRQYC PVCGSMPVSS MVQIGTTQGL RYLHCNLCET EWHVVRVKCS NCEQSGKLHY
     WSLDDEQAAI KAESCDDCDT YLKILYQEKD PKIEAVADDL ASLVLDARME QEGYARSSIN
     PFLFPGEGE