ID   FDHE_ECOLI              Reviewed;         309 AA.
AC   P13024; Q2M8I8;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 2.
DT   03-AUG-2022, entry version 161.
DE   RecName: Full=Protein FdhE;
GN   Name=fdhE; OrderedLocusNames=b3891, JW3862;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=1995428; DOI=10.1016/0378-1119(91)90023-5;
RA   Schlindwein C., Mandrand M.-A.;
RT   "Nucleotide sequence of the fdhE gene involved in respiratory formate
RT   dehydrogenase formation in Escherichia coli K-12.";
RL   Gene 97:147-148(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=8346018; DOI=10.1093/nar/21.15.3391;
RA   Plunkett G. III, Burland V., Daniels D.L., Blattner F.R.;
RT   "Analysis of the Escherichia coli genome. III. DNA sequence of the region
RT   from 87.2 to 89.2 minutes.";
RL   Nucleic Acids Res. 21:3391-3398(1993).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- FUNCTION: Necessary for formate dehydrogenase activity.
CC   -!- INTERACTION:
CC       P13024; P24183: fdnG; NbExp=6; IntAct=EBI-550129, EBI-550115;
CC       P13024; P32176: fdoG; NbExp=4; IntAct=EBI-550129, EBI-368676;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the FdhE family. {ECO:0000305}.
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DR   EMBL; X16016; CAA34149.1; -; Genomic_DNA.
DR   EMBL; L19201; AAB03024.1; -; Genomic_DNA.
DR   EMBL; U00096; AAD13453.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77418.1; -; Genomic_DNA.
DR   PIR; S40835; S40835.
DR   RefSeq; NP_418327.1; NC_000913.3.
DR   RefSeq; WP_000027703.1; NZ_SSZK01000026.1.
DR   AlphaFoldDB; P13024; -.
DR   SMR; P13024; -.
DR   BioGRID; 4261097; 13.
DR   BioGRID; 852681; 1.
DR   DIP; DIP-9571N; -.
DR   IntAct; P13024; 26.
DR   MINT; P13024; -.
DR   STRING; 511145.b3891; -.
DR   jPOST; P13024; -.
DR   PaxDb; P13024; -.
DR   PRIDE; P13024; -.
DR   EnsemblBacteria; AAD13453; AAD13453; b3891.
DR   EnsemblBacteria; BAE77418; BAE77418; BAE77418.
DR   GeneID; 948384; -.
DR   KEGG; ecj:JW3862; -.
DR   KEGG; eco:b3891; -.
DR   PATRIC; fig|1411691.4.peg.2818; -.
DR   EchoBASE; EB0280; -.
DR   eggNOG; COG3058; Bacteria.
DR   HOGENOM; CLU_055275_0_0_6; -.
DR   InParanoid; P13024; -.
DR   OMA; PKNLYQR; -.
DR   PhylomeDB; P13024; -.
DR   BioCyc; EcoCyc:EG10284-MON; -.
DR   PRO; PR:P13024; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IDA:EcoCyc.
DR   GO; GO:0005829; C:cytosol; IDA:EcoCyc.
DR   GO; GO:0008199; F:ferric iron binding; IDA:EcoCyc.
DR   GO; GO:0051604; P:protein maturation; IMP:EcoCyc.
DR   CDD; cd16341; FdhE; 1.
DR   Gene3D; 3.90.1670.10; -; 1.
DR   HAMAP; MF_00611; FdeH; 1.
DR   InterPro; IPR024064; FdhE-like_sf.
DR   InterPro; IPR006452; Formate_DH_accessory.
DR   PANTHER; PTHR37689; PTHR37689; 1.
DR   Pfam; PF04216; FdhE; 1.
DR   PIRSF; PIRSF018296; Format_dh_formtn; 1.
DR   SUPFAM; SSF144020; SSF144020; 1.
DR   TIGRFAMs; TIGR01562; FdhE; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..309
FT                   /note="Protein FdhE"
FT                   /id="PRO_0000189638"
FT   CONFLICT        57
FT                   /note="A -> R (in Ref. 1; CAA34149)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        177..208
FT                   /note="GKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQ -> AKPALNTASNVNIARF
FT                   VVLCRCPAWCKLAPLR (in Ref. 1; CAA34149)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        291
FT                   /note="Q -> E (in Ref. 1; CAA34149)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        296..309
FT                   /note="RSSINPFLFPGEGE -> AVPSTRSCFRVKESNL (in Ref. 1;
FT                   CAA34149)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   309 AA;  34747 MW;  F9A0B30CC980D6E6 CRC64;
     MSIRIIPQDE LGSSEKRTAD MIPPLLFPRL KNLYNRRAER LRELAENNPL GDYLRFAALI
     AHAQEVVLYD HPLEMDLTAR IKEASAQGKP PLDIHVLPRD KHWQKLLMAL IAELKPEMSG
     PALAVIENLE KASTQELEDM ASALFASDFS SVSSDKAPFI WAALSLYWAQ MANLIPGKAR
     AEYGEQRQYC PVCGSMPVSS MVQIGTTQGL RYLHCNLCET EWHVVRVKCS NCEQSGKLHY
     WSLDDEQAAI KAESCDDCDT YLKILYQEKD PKIEAVADDL ASLVLDARME QEGYARSSIN
     PFLFPGEGE