ID   FDHE_ECOUT              Reviewed;         309 AA.
AC   Q1R424;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Protein FdhE {ECO:0000255|HAMAP-Rule:MF_00611};
GN   Name=fdhE {ECO:0000255|HAMAP-Rule:MF_00611}; OrderedLocusNames=UTI89_C4478;
OS   Escherichia coli (strain UTI89 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=364106;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UTI89 / UPEC;
RX   PubMed=16585510; DOI=10.1073/pnas.0600938103;
RA   Chen S.L., Hung C.-S., Xu J., Reigstad C.S., Magrini V., Sabo A.,
RA   Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R., Fulton R.S.,
RA   Latreille J.P., Spieth J., Hooton T.M., Mardis E.R., Hultgren S.J.,
RA   Gordon J.I.;
RT   "Identification of genes subject to positive selection in uropathogenic
RT   strains of Escherichia coli: a comparative genomics approach.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2006).
CC   -!- FUNCTION: Necessary for formate dehydrogenase activity.
CC       {ECO:0000255|HAMAP-Rule:MF_00611}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00611}.
CC   -!- SIMILARITY: Belongs to the FdhE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00611}.
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DR   EMBL; CP000243; ABE09890.1; -; Genomic_DNA.
DR   RefSeq; WP_000027720.1; NC_007946.1.
DR   AlphaFoldDB; Q1R424; -.
DR   SMR; Q1R424; -.
DR   EnsemblBacteria; ABE09890; ABE09890; UTI89_C4478.
DR   KEGG; eci:UTI89_C4478; -.
DR   HOGENOM; CLU_055275_0_0_6; -.
DR   OMA; PKNLYQR; -.
DR   Proteomes; UP000001952; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   CDD; cd16341; FdhE; 1.
DR   Gene3D; 3.90.1670.10; -; 1.
DR   HAMAP; MF_00611; FdeH; 1.
DR   InterPro; IPR024064; FdhE-like_sf.
DR   InterPro; IPR006452; Formate_DH_accessory.
DR   PANTHER; PTHR37689; PTHR37689; 1.
DR   Pfam; PF04216; FdhE; 1.
DR   PIRSF; PIRSF018296; Format_dh_formtn; 1.
DR   SUPFAM; SSF144020; SSF144020; 1.
DR   TIGRFAMs; TIGR01562; FdhE; 1.
PE   3: Inferred from homology;
KW   Cytoplasm.
FT   CHAIN           1..309
FT                   /note="Protein FdhE"
FT                   /id="PRO_1000056701"
SQ   SEQUENCE   309 AA;  34719 MW;  59F4BEED1D26D0DC CRC64;
     MSIRIIPQDE LGSSEKRTAD MIPPLLFPRL KNLYNRRAER LRELAENNPL GDYLRFAALI
     AHAQEVVLYD HPLEMDLTTR IKEASAQGKP PLDIHVLPRD KHWQKLLMAL IAELKPEMSG
     PALAVIENLE KASTQELEDM ASALFASDFS SVSSDKAPFI WAALSLYWAQ MANLIPGKAR
     AEYGEQRQYC PVCGSMPVSS MVQIGTTQGL RYLHCNLCET EWHVVRVKCS NCEQSGKLHY
     WSLDDEQAAI KAESCDDCGT YLKILYQEKE PKVEAVADDL ASLVLDARME QEGYARSSIN
     PFLFPGEGE