ID   FDHE_HAEI8              Reviewed;         302 AA.
AC   Q4QPN5;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Protein FdhE homolog {ECO:0000255|HAMAP-Rule:MF_00611};
GN   Name=fdhE {ECO:0000255|HAMAP-Rule:MF_00611}; OrderedLocusNames=NTHI0012;
OS   Haemophilus influenzae (strain 86-028NP).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=281310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=86-028NP;
RX   PubMed=15968074; DOI=10.1128/jb.187.13.4627-4636.2005;
RA   Harrison A., Dyer D.W., Gillaspy A., Ray W.C., Mungur R., Carson M.B.,
RA   Zhong H., Gipson J., Gipson M., Johnson L.S., Lewis L., Bakaletz L.O.,
RA   Munson R.S. Jr.;
RT   "Genomic sequence of an otitis media isolate of nontypeable Haemophilus
RT   influenzae: comparative study with H. influenzae serotype d, strain KW20.";
RL   J. Bacteriol. 187:4627-4636(2005).
CC   -!- FUNCTION: Necessary for formate dehydrogenase activity.
CC       {ECO:0000255|HAMAP-Rule:MF_00611}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00611}.
CC   -!- SIMILARITY: Belongs to the FdhE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00611}.
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DR   EMBL; CP000057; AAX87012.1; -; Genomic_DNA.
DR   RefSeq; WP_011271779.1; NC_007146.2.
DR   AlphaFoldDB; Q4QPN5; -.
DR   SMR; Q4QPN5; -.
DR   EnsemblBacteria; AAX87012; AAX87012; NTHI0012.
DR   KEGG; hit:NTHI0012; -.
DR   HOGENOM; CLU_055275_0_0_6; -.
DR   OMA; PKNLYQR; -.
DR   OrthoDB; 876348at2; -.
DR   Proteomes; UP000002525; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   CDD; cd16341; FdhE; 1.
DR   Gene3D; 3.90.1670.10; -; 1.
DR   HAMAP; MF_00611; FdeH; 1.
DR   InterPro; IPR024064; FdhE-like_sf.
DR   InterPro; IPR006452; Formate_DH_accessory.
DR   PANTHER; PTHR37689; PTHR37689; 1.
DR   Pfam; PF04216; FdhE; 1.
DR   PIRSF; PIRSF018296; Format_dh_formtn; 1.
DR   SUPFAM; SSF144020; SSF144020; 1.
DR   TIGRFAMs; TIGR01562; FdhE; 1.
PE   3: Inferred from homology;
KW   Cytoplasm.
FT   CHAIN           1..302
FT                   /note="Protein FdhE homolog"
FT                   /id="PRO_1000056704"
SQ   SEQUENCE   302 AA;  34163 MW;  C7D8F6AED2F2D8F3 CRC64;
     MSIKILSESE IKQVANSYQA PAVLFANPKN LYQRRAKRLR DLAQNHPLSD YLLFAADIVE
     SQLSTLEKNP LPPQQLEQLN AIEPLNAKTF KRDSIWREYL TEILDEIKPK ANEQIAATIE
     FLEKASSAEL EEMANKLLAQ EFNLVSSDKA VFIWAALSLY WLQAAQQIPH NSQVENAENL
     HHCPVCGSLP VASIVQIGTS QGLRYLHCNL CESEWNLVRA QCTNCNSHDK LEMWSLNEEL
     ALVRAETCGS CESYLKMMFQ EKDPYVEPVA DDLASIFLDI EMEEKGFARS GLNPFIFPAE
     DA