ID   FDHE_SHIFL              Reviewed;         309 AA.
AC   Q83PE8;
DT   26-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=Protein FdhE homolog {ECO:0000255|HAMAP-Rule:MF_00611};
GN   Name=fdhE {ECO:0000255|HAMAP-Rule:MF_00611};
GN   OrderedLocusNames=SF3967, S3781;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: Necessary for formate dehydrogenase activity.
CC       {ECO:0000255|HAMAP-Rule:MF_00611}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00611}.
CC   -!- SIMILARITY: Belongs to the FdhE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00611}.
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DR   EMBL; AE005674; AAN45402.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP18798.1; -; Genomic_DNA.
DR   RefSeq; NP_709695.1; NC_004337.2.
DR   RefSeq; WP_000027722.1; NZ_WPGW01000130.1.
DR   AlphaFoldDB; Q83PE8; -.
DR   SMR; Q83PE8; -.
DR   STRING; 198214.SF3967; -.
DR   EnsemblBacteria; AAN45402; AAN45402; SF3967.
DR   EnsemblBacteria; AAP18798; AAP18798; S3781.
DR   GeneID; 1023632; -.
DR   GeneID; 58391683; -.
DR   KEGG; sfl:SF3967; -.
DR   KEGG; sfx:S3781; -.
DR   PATRIC; fig|198214.7.peg.4675; -.
DR   HOGENOM; CLU_055275_0_0_6; -.
DR   OMA; PKNLYQR; -.
DR   OrthoDB; 876348at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   CDD; cd16341; FdhE; 1.
DR   Gene3D; 3.90.1670.10; -; 1.
DR   HAMAP; MF_00611; FdeH; 1.
DR   InterPro; IPR024064; FdhE-like_sf.
DR   InterPro; IPR006452; Formate_DH_accessory.
DR   PANTHER; PTHR37689; PTHR37689; 1.
DR   Pfam; PF04216; FdhE; 1.
DR   PIRSF; PIRSF018296; Format_dh_formtn; 1.
DR   SUPFAM; SSF144020; SSF144020; 1.
DR   TIGRFAMs; TIGR01562; FdhE; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..309
FT                   /note="Protein FdhE homolog"
FT                   /id="PRO_0000189651"
SQ   SEQUENCE   309 AA;  34688 MW;  FEC5A447B506D7DD CRC64;
     MSIRIIPQDE LGSSEKRTAD MIPPLLFPRL KNLYNRRAER LRELAENNPL GDYLRFAALI
     AHAQKVVLYD HPLEMDLTAR IKEASAQGKP PLDIHVLPRD KHWQKLLMAL IAELKPEMSG
     PALAVIENLE KASTQELEDM ASALFASDFS SVSSDKAPFI WAALSLYWAQ MANLIPGKAR
     AEYGEQRQYC PVCGSMPVSS MVQIGTTQGL RYLHCNLCET EWHVVRVKCS NCEQSGKLHY
     WSLDDEQAAI KAESCDDCGT YLKILYQEKE PKVEAVADDL ASLVLDARME QEGYARSSIN
     PFLFPGEGE