ID   AIPL1_PANPA             Reviewed;         384 AA.
AC   Q95MN9;
DT   28-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Aryl-hydrocarbon-interacting protein-like 1;
GN   Name=AIPL1;
OS   Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9597;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=11420621; DOI=10.1007/s003350020024;
RA   Sohocki M.M., Sullivan L.S., Tirpak D.L., Daiger S.P.;
RT   "Comparative analysis of aryl-hydrocarbon receptor interacting protein-like
RT   1 (Aipl1), a gene associated with inherited retinal disease in humans.";
RL   Mamm. Genome 12:566-568(2001).
CC   -!- FUNCTION: May be important in protein trafficking and/or protein
CC       folding and stabilization. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with NUB1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
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DR   EMBL; AF296413; AAK77957.1; -; mRNA.
DR   RefSeq; NP_001266158.1; NM_001279229.1.
DR   AlphaFoldDB; Q95MN9; -.
DR   SMR; Q95MN9; -.
DR   STRING; 9597.NP_001266158.1; -.
DR   GeneID; 100970167; -.
DR   KEGG; pps:100970167; -.
DR   CTD; 23746; -.
DR   eggNOG; KOG0545; Eukaryota.
DR   OrthoDB; 897391at2759; -.
DR   Proteomes; UP000240080; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:InterPro.
DR   GO; GO:0007601; P:visual perception; IEA:InterPro.
DR   Gene3D; 1.25.40.10; -; 1.
DR   Gene3D; 3.10.50.40; -; 1.
DR   InterPro; IPR039663; AIP/AIPL1.
DR   InterPro; IPR031209; AIPL1.
DR   InterPro; IPR046357; PPIase_dom_sf.
DR   InterPro; IPR001179; PPIase_FKBP_dom.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR11242; PTHR11242; 1.
DR   PANTHER; PTHR11242:SF2; PTHR11242:SF2; 1.
DR   Pfam; PF00254; FKBP_C; 1.
DR   SMART; SM00028; TPR; 2.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   PROSITE; PS50293; TPR_REGION; 2.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Reference proteome; Repeat; TPR repeat.
FT   CHAIN           1..384
FT                   /note="Aryl-hydrocarbon-interacting protein-like 1"
FT                   /id="PRO_0000075345"
FT   DOMAIN          53..145
FT                   /note="PPIase FKBP-type"
FT   REPEAT          178..211
FT                   /note="TPR 1"
FT   REPEAT          230..263
FT                   /note="TPR 2"
FT   REPEAT          264..297
FT                   /note="TPR 3"
FT   REGION          328..384
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        335..362
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   384 AA;  43931 MW;  4509535CF70316E9 CRC64;
     MDAALLLNVE GVKKTILHGG TGELPNFITG SRVIFHFRTM KCDEERTVID DSRQVGQPMH
     IIIGNMFKLE VWEILLTSMR VHEVAEFWCD TIHTGVYPIL SRSLRQMAQG KDPTEWHVHT
     CGLANMFAYH TLGYEDLDEL QKEPQPLVFV IELLQVDAPS DYQRETWNLS NHEKMKAVPV
     LHGEGNRLFK LGRYEEASSK YQEAIICLRN LQTKEKPWEV QWLKLEKMIN TLILNYCQCL
     LKKEEYYEVL EHTSDILRHH PGIVKAYYVR ARAHAEVWNE AEAKADLRKV LELEPSMQKA
     VRRELRLLEN RMAEKQEEER LRCRNMLSQG ATQPPAEPPT EPPAQSSTEP PAEPPPAPSA
     ELSAGPPAET ATEPPPSPGH SLQH