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AIPL1_PAPCY
ID   AIPL1_PAPCY             Reviewed;         372 AA.
AC   Q95MN8;
DT   10-MAY-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Aryl-hydrocarbon-interacting protein-like 1;
GN   Name=AIPL1;
OS   Papio cynocephalus (Yellow baboon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Papio.
OX   NCBI_TaxID=9556;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=11420621; DOI=10.1007/s003350020024;
RA   Sohocki M.M., Sullivan L.S., Tirpak D.L., Daiger S.P.;
RT   "Comparative analysis of aryl-hydrocarbon receptor interacting protein-like
RT   1 (Aipl1), a gene associated with inherited retinal disease in humans.";
RL   Mamm. Genome 12:566-568(2001).
CC   -!- FUNCTION: May be important in protein trafficking and/or protein
CC       folding and stabilization. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with NUB1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
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DR   EMBL; AF296414; AAK77958.1; -; mRNA.
DR   AlphaFoldDB; Q95MN8; -.
DR   SMR; Q95MN8; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:InterPro.
DR   GO; GO:0007601; P:visual perception; IEA:InterPro.
DR   Gene3D; 1.25.40.10; -; 1.
DR   Gene3D; 3.10.50.40; -; 1.
DR   InterPro; IPR039663; AIP/AIPL1.
DR   InterPro; IPR031209; AIPL1.
DR   InterPro; IPR046357; PPIase_dom_sf.
DR   InterPro; IPR001179; PPIase_FKBP_dom.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR11242; PTHR11242; 1.
DR   PANTHER; PTHR11242:SF2; PTHR11242:SF2; 1.
DR   Pfam; PF00254; FKBP_C; 1.
DR   SMART; SM00028; TPR; 2.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   PROSITE; PS50293; TPR_REGION; 2.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Repeat; TPR repeat.
FT   CHAIN           1..372
FT                   /note="Aryl-hydrocarbon-interacting protein-like 1"
FT                   /id="PRO_0000075346"
FT   DOMAIN          53..145
FT                   /note="PPIase FKBP-type"
FT   REPEAT          178..211
FT                   /note="TPR 1"
FT   REPEAT          230..263
FT                   /note="TPR 2"
FT   REPEAT          264..297
FT                   /note="TPR 3"
FT   REGION          315..372
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        335..362
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   372 AA;  42907 MW;  FB4512AAFAA9E307 CRC64;
     MDAALLLNVE GVKKTILHGG TGELPNFITG SRVIFHFRTM KCDEERTVID DSRQVDQPMH
     IIIGNMFKLE VWEILLTSMR VHEVAEFWCD TIHTGVYPIL SRSLRQMAQG KDPTEWHVHT
     CGLANMFAYH TLGYEDLDEL QKEPQPLIFV IELLQVDAPS DYQRETWNLS NHEKMKVVPV
     LHGEGNRLFK LGRYEEASSK YQEAIICLRN LQTKEKPWEV QWLKLEKMIN TLTLNYCQCL
     LKKEEYYEVL EHTSDILRHH PGIVKAYYVR ARAHAEVWNE AEAKADLQKV LELEPSMQKA
     VRRELRLLEN RMAEKQEEER LRCRNMLSQG ATQPPTEPPA EPHTAPPAEL STGPPAEPPA
     ELPLSPGHSL QH
 
 
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