ID   FDL31_ARATH             Reviewed;         450 AA.
AC   Q9FNJ5; A8MSB2;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=F-box/FBD/LRR-repeat protein At5g22660;
GN   OrderedLocusNames=At5g22660; ORFNames=MDJ22.8;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9405937; DOI=10.1093/dnares/4.4.291;
RA   Kotani H., Nakamura Y., Sato S., Kaneko T., Asamizu E., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. II. Sequence
RT   features of the regions of 1,044,062 bp covered by thirteen physically
RT   assigned P1 clones.";
RL   DNA Res. 4:291-300(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC   STRAIN=cv. Columbia;
RX   PubMed=14993207; DOI=10.1101/gr.1515604;
RA   Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA   Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA   Weissenbach J., Salanoubat M.;
RT   "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT   combined approach to evaluate and improve Arabidopsis genome annotation.";
RL   Genome Res. 14:406-413(2004).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q9FNJ5-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q9FNJ5-2; Sequence=VSP_035541, VSP_035542;
CC   -!- MISCELLANEOUS: [Isoform 2]: May be due to an intron retention.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BX831572; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
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DR   EMBL; AB006699; BAB11672.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED93060.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED93061.1; -; Genomic_DNA.
DR   EMBL; BX831572; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; NP_001078614.1; NM_001085145.2. [Q9FNJ5-1]
DR   RefSeq; NP_197658.2; NM_122172.3. [Q9FNJ5-2]
DR   AlphaFoldDB; Q9FNJ5; -.
DR   PaxDb; Q9FNJ5; -.
DR   PRIDE; Q9FNJ5; -.
DR   EnsemblPlants; AT5G22660.1; AT5G22660.1; AT5G22660. [Q9FNJ5-2]
DR   EnsemblPlants; AT5G22660.2; AT5G22660.2; AT5G22660. [Q9FNJ5-1]
DR   GeneID; 832329; -.
DR   Gramene; AT5G22660.1; AT5G22660.1; AT5G22660. [Q9FNJ5-2]
DR   Gramene; AT5G22660.2; AT5G22660.2; AT5G22660. [Q9FNJ5-1]
DR   KEGG; ath:AT5G22660; -.
DR   Araport; AT5G22660; -.
DR   TAIR; locus:2162489; AT5G22660.
DR   eggNOG; ENOG502T0EG; Eukaryota.
DR   HOGENOM; CLU_010721_1_3_1; -.
DR   InParanoid; Q9FNJ5; -.
DR   OMA; ACEINVV; -.
DR   OrthoDB; 686125at2759; -.
DR   PhylomeDB; Q9FNJ5; -.
DR   PRO; PR:Q9FNJ5; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FNJ5; baseline and differential.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR006566; FBD.
DR   InterPro; IPR013101; Leu-rich_rpt_2.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   Pfam; PF00646; F-box; 1.
DR   Pfam; PF08387; FBD; 1.
DR   Pfam; PF07723; LRR_2; 1.
DR   SMART; SM00579; FBD; 1.
DR   SMART; SM00256; FBOX; 1.
DR   SUPFAM; SSF81383; SSF81383; 1.
DR   PROSITE; PS50181; FBOX; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Leucine-rich repeat; Reference proteome; Repeat.
FT   CHAIN           1..450
FT                   /note="F-box/FBD/LRR-repeat protein At5g22660"
FT                   /id="PRO_0000283123"
FT   DOMAIN          12..58
FT                   /note="F-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT   REPEAT          157..181
FT                   /note="LRR 1"
FT   REPEAT          294..317
FT                   /note="LRR 2"
FT   DOMAIN          364..416
FT                   /note="FBD"
FT   VAR_SEQ         309..315
FT                   /note="IICHYLK -> VYMHTNI (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:14993207"
FT                   /id="VSP_035541"
FT   VAR_SEQ         316..450
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:14993207"
FT                   /id="VSP_035542"
SQ   SEQUENCE   450 AA;  51626 MW;  95AABE29D0486044 CRC64;
     MSNQGAIRRS GEDRISSLPD HLLSQILSNL PTENAVTTSI LSTRWKDLWL STPVLDIDID
     AFDDATTFIS FATRFLDSFK DSCLHKLQIS FQMEAVDMWT IIPWIEDAVK RRIQHLEVDS
     RIDHMIDTLP LTVYLSESLV SLRLHLVMLH RFVFVSLPNL KVMHLEENIY SYAETMEKFI
     SSCPVLEDLT VVRNVDEATE KVLRVSSQSL NSLKLVIDSS KCWYNDDSDD WKVVIDAPQL
     VYLSLKDDQS VSFVINNLCS SAKADIKVSF NVSDIWDLEE SFERSNVGKF LTGLSSLRDM
     TISGTTLKII CHYLKHEPMP QFRNMTRLHA KFYVCDLEML PCVLESCPNL KSLVLKLKGE
     MENEEISLSS SVPKCLQSSL ENVEIIRPNY GSGEEMKLSK YFLENSLVLK KFKLCRDCHS
     EEQESLVVRE LMTFQRCSSA CEINVVRFQR