AIR1_ARATH
ID AIR1_ARATH Reviewed; 111 AA.
AC Q9S7I2; Q8LDJ2;
DT 11-JUN-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 128.
DE RecName: Full=Putative lipid-binding protein AIR1;
DE AltName: Full=Auxin-induced in root cultures protein 1;
DE Flags: Precursor;
GN Name=AIR1; Synonyms=AIR1A; OrderedLocusNames=At4g12550; ORFNames=T1P17.140;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], DEVELOPMENTAL STAGE, AND INDUCTION.
RC STRAIN=cv. Columbia;
RX PubMed=10080694; DOI=10.1023/a:1006104205959;
RA Neuteboom L.W., Ng J.M.Y., Kuyper M., Clijdesdale O.R., Hooykaas P.J.J.,
RA van der Zaal B.J.;
RT "Isolation and characterization of cDNA clones corresponding with mRNAs
RT that accumulate during auxin-induced lateral root formation.";
RL Plant Mol. Biol. 39:273-287(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- DEVELOPMENTAL STAGE: Expressed during auxin-induced lateral root
CC formation. {ECO:0000269|PubMed:10080694}.
CC -!- INDUCTION: Induced between 4 and 8 hours after treatment with auxin and
CC remains high for at least 24 hours. {ECO:0000269|PubMed:10080694}.
CC -!- SIMILARITY: Belongs to the plant LTP family. PEARLI1 subfamily.
CC {ECO:0000305}.
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DR EMBL; AF098630; AAD12258.1; -; Genomic_DNA.
DR EMBL; AL049730; CAB41725.1; -; Genomic_DNA.
DR EMBL; AL161534; CAB78298.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE83146.1; -; Genomic_DNA.
DR EMBL; AF410287; AAK95273.1; -; mRNA.
DR EMBL; AY093728; AAM10352.1; -; mRNA.
DR EMBL; AY085981; AAM63191.1; -; mRNA.
DR PIR; T07647; T07647.
DR RefSeq; NP_192992.1; NM_117325.2.
DR AlphaFoldDB; Q9S7I2; -.
DR SMR; Q9S7I2; -.
DR STRING; 3702.AT4G12550.1; -.
DR PaxDb; Q9S7I2; -.
DR EnsemblPlants; AT4G12550.1; AT4G12550.1; AT4G12550.
DR GeneID; 826868; -.
DR Gramene; AT4G12550.1; AT4G12550.1; AT4G12550.
DR KEGG; ath:AT4G12550; -.
DR Araport; AT4G12550; -.
DR TAIR; locus:2135600; AT4G12550.
DR eggNOG; ENOG502RZES; Eukaryota.
DR HOGENOM; CLU_055715_1_2_1; -.
DR InParanoid; Q9S7I2; -.
DR OMA; CPKNSIE; -.
DR OrthoDB; 1608612at2759; -.
DR PhylomeDB; Q9S7I2; -.
DR PRO; PR:Q9S7I2; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9S7I2; baseline and differential.
DR Genevisible; Q9S7I2; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0010102; P:lateral root morphogenesis; IEP:TAIR.
DR GO; GO:0009733; P:response to auxin; IEP:TAIR.
DR CDD; cd01958; HPS_like; 1.
DR Gene3D; 1.10.110.10; -; 1.
DR InterPro; IPR036312; Bifun_inhib/LTP/seed_sf.
DR InterPro; IPR016140; Bifunc_inhib/LTP/seed_store.
DR InterPro; IPR027923; Hydrophob_seed_dom.
DR Pfam; PF14547; Hydrophob_seed; 1.
DR SMART; SM00499; AAI; 1.
DR SUPFAM; SSF47699; SSF47699; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond; Reference proteome; Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..111
FT /note="Putative lipid-binding protein AIR1"
FT /id="PRO_0000429358"
FT DISULFID 28..58
FT /evidence="ECO:0000255"
FT DISULFID 38..57
FT /evidence="ECO:0000255"
FT DISULFID 74..110
FT /evidence="ECO:0000255"
FT CONFLICT 77
FT /note="V -> L (in Ref. 5; AAM63191)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 111 AA; 11624 MW; 8A5F3D2450FA90CC CRC64;
MAPRTPLALF VSLNLLFFTY TSATTGTCPK NSIEIGTCVT VLNLVDLTLG NPPVKPCCSL
IQGLADLEAA VCLCTAVKAS ILGIVNINLP INLSVLLNVC SRNAPKSFQC A
