FEOA_CAMJE
ID FEOA_CAMJE Reviewed; 74 AA.
AC Q9PMR0; Q0P8L7;
DT 27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=Putative Fe(2+) transport protein A {ECO:0000303|PubMed:16988218};
GN Name=feoA {ECO:0000303|PubMed:16988218}; OrderedLocusNames=Cj1397;
OS Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC
OS 11168).
OC Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC Campylobacteraceae; Campylobacter.
OX NCBI_TaxID=192222;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700819 / NCTC 11168;
RX PubMed=10688204; DOI=10.1038/35001088;
RA Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M.,
RA Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S.,
RA Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A.,
RA Rajandream M.A., Rutherford K.M., van Vliet A.H.M., Whitehead S.,
RA Barrell B.G.;
RT "The genome sequence of the food-borne pathogen Campylobacter jejuni
RT reveals hypervariable sequences.";
RL Nature 403:665-668(2000).
RN [2]
RP INDUCTION, AND OPERON.
RC STRAIN=ATCC 700819 / NCTC 11168;
RX PubMed=16988218; DOI=10.1128/iai.00052-06;
RA Naikare H., Palyada K., Panciera R., Marlow D., Stintzi A.;
RT "Major role for FeoB in Campylobacter jejuni ferrous iron acquisition, gut
RT colonization, and intracellular survival.";
RL Infect. Immun. 74:5433-5444(2006).
CC -!- FUNCTION: Might be involved in Fe(2+) ion uptake (By similarity).
CC {ECO:0000250|UniProtKB:P0AEL3}.
CC -!- INDUCTION: Detected in iron-restricted, mid-log-phase cells, part of
CC the feoA-feoB operon (strain NCTC 11168).
CC {ECO:0000269|PubMed:16988218}.
CC -!- SIMILARITY: Belongs to the FeoA family. {ECO:0000305}.
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DR EMBL; AL111168; CAL35506.1; -; Genomic_DNA.
DR PIR; E81284; E81284.
DR RefSeq; WP_002779147.1; NC_002163.1.
DR RefSeq; YP_002344780.1; NC_002163.1.
DR AlphaFoldDB; Q9PMR0; -.
DR SMR; Q9PMR0; -.
DR IntAct; Q9PMR0; 4.
DR STRING; 192222.Cj1397; -.
DR PaxDb; Q9PMR0; -.
DR PRIDE; Q9PMR0; -.
DR EnsemblBacteria; CAL35506; CAL35506; Cj1397.
DR GeneID; 905686; -.
DR KEGG; cje:Cj1397; -.
DR PATRIC; fig|192222.6.peg.1378; -.
DR eggNOG; COG1918; Bacteria.
DR HOGENOM; CLU_150646_12_2_7; -.
DR OMA; IRSSMAN; -.
DR PRO; PR:Q9PMR0; -.
DR Proteomes; UP000000799; Chromosome.
DR GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR Gene3D; 2.30.30.90; -; 1.
DR InterPro; IPR007167; Fe-transptr_FeoA.
DR InterPro; IPR038157; FeoA_core_dom.
DR InterPro; IPR008988; Transcriptional_repressor_C.
DR Pfam; PF04023; FeoA; 1.
DR SMART; SM00899; FeoA; 1.
DR SUPFAM; SSF50037; SSF50037; 1.
PE 2: Evidence at transcript level;
KW Ion transport; Iron; Iron transport; Reference proteome; Transport.
FT CHAIN 1..74
FT /note="Putative Fe(2+) transport protein A"
FT /id="PRO_0000128693"
SQ SEQUENCE 74 AA; 8363 MW; EB1BC8AE3690DCD4 CRC64;
MTLNELKDGQ KAIIVNLNAH KELKNRLLSF GFIKNKNLKK IHSSLKNATI MVELDTSCVI
LRSDEAKTIE VNLI