ID   FEOC_ECO24              Reviewed;          78 AA.
AC   A7ZST9;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Probable [Fe-S]-dependent transcriptional repressor {ECO:0000255|HAMAP-Rule:MF_01586};
GN   Name=feoC {ECO:0000255|HAMAP-Rule:MF_01586};
GN   OrderedLocusNames=EcE24377A_3885;
OS   Escherichia coli O139:H28 (strain E24377A / ETEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=331111;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E24377A / ETEC;
RX   PubMed=18676672; DOI=10.1128/jb.00619-08;
RA   Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F.,
RA   Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R.,
RA   Henderson I.R., Sperandio V., Ravel J.;
RT   "The pangenome structure of Escherichia coli: comparative genomic analysis
RT   of E. coli commensal and pathogenic isolates.";
RL   J. Bacteriol. 190:6881-6893(2008).
CC   -!- FUNCTION: May function as a transcriptional regulator that controls
CC       feoABC expression. {ECO:0000255|HAMAP-Rule:MF_01586}.
CC   -!- SIMILARITY: Belongs to the FeoC family. {ECO:0000255|HAMAP-
CC       Rule:MF_01586}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000800; ABV17802.1; -; Genomic_DNA.
DR   RefSeq; WP_001352764.1; NC_009801.1.
DR   AlphaFoldDB; A7ZST9; -.
DR   BMRB; A7ZST9; -.
DR   SMR; A7ZST9; -.
DR   EnsemblBacteria; ABV17802; ABV17802; EcE24377A_3885.
DR   KEGG; ecw:EcE24377A_3885; -.
DR   HOGENOM; CLU_189182_0_0_6; -.
DR   OMA; CLSGGCK; -.
DR   Proteomes; UP000001122; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_01586; FeoC; 1.
DR   InterPro; IPR023732; FeoC.
DR   InterPro; IPR015102; Tscrpt_reg_HTH_FeoC.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF09012; FeoC; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Iron; Iron-sulfur; Metal-binding; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..78
FT                   /note="Probable [Fe-S]-dependent transcriptional repressor"
FT                   /id="PRO_1000069315"
FT   BINDING         56
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
FT   BINDING         61
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
FT   BINDING         64
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
FT   BINDING         70
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
SQ   SEQUENCE   78 AA;  8659 MW;  80B76DE222A70245 CRC64;
     MASLIQVRDL LALRGRMKAA QISQTLNTPQ PMINAMLQQL ESMGKAVRIQ EEPDGCLSGS
     CKSCPEGKAC LREWWALR