ID   FEOC_ECOHS              Reviewed;          78 AA.
AC   A8A5L8;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Probable [Fe-S]-dependent transcriptional repressor {ECO:0000255|HAMAP-Rule:MF_01586};
GN   Name=feoC {ECO:0000255|HAMAP-Rule:MF_01586}; OrderedLocusNames=EcHS_A3607;
OS   Escherichia coli O9:H4 (strain HS).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=331112;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HS;
RX   PubMed=18676672; DOI=10.1128/jb.00619-08;
RA   Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F.,
RA   Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R.,
RA   Henderson I.R., Sperandio V., Ravel J.;
RT   "The pangenome structure of Escherichia coli: comparative genomic analysis
RT   of E. coli commensal and pathogenic isolates.";
RL   J. Bacteriol. 190:6881-6893(2008).
CC   -!- FUNCTION: May function as a transcriptional regulator that controls
CC       feoABC expression. {ECO:0000255|HAMAP-Rule:MF_01586}.
CC   -!- SIMILARITY: Belongs to the FeoC family. {ECO:0000255|HAMAP-
CC       Rule:MF_01586}.
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DR   EMBL; CP000802; ABV07822.1; -; Genomic_DNA.
DR   RefSeq; WP_001295699.1; NC_009800.1.
DR   AlphaFoldDB; A8A5L8; -.
DR   BMRB; A8A5L8; -.
DR   SMR; A8A5L8; -.
DR   GeneID; 58460229; -.
DR   KEGG; ecx:EcHS_A3607; -.
DR   HOGENOM; CLU_189182_0_0_6; -.
DR   OMA; CLSGGCK; -.
DR   Proteomes; UP000001123; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_01586; FeoC; 1.
DR   InterPro; IPR023732; FeoC.
DR   InterPro; IPR015102; Tscrpt_reg_HTH_FeoC.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF09012; FeoC; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Iron; Iron-sulfur; Metal-binding; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..78
FT                   /note="Probable [Fe-S]-dependent transcriptional repressor"
FT                   /id="PRO_1000069316"
FT   BINDING         56
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
FT   BINDING         61
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
FT   BINDING         64
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
FT   BINDING         70
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
SQ   SEQUENCE   78 AA;  8690 MW;  889778F72CBC174B CRC64;
     MASLIQVRDL LALRGRMEAT QISQTLNTPQ PMINAMLQQL ESMGKAVRIQ EEPDGCLSGS
     CKSCPEGKAC LREWWALR