FEOC_ECOK1
ID FEOC_ECOK1 Reviewed; 78 AA.
AC P0C602;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-JAN-2008, sequence version 1.
DT 03-AUG-2022, entry version 47.
DE RecName: Full=Probable [Fe-S]-dependent transcriptional repressor {ECO:0000255|HAMAP-Rule:MF_01586};
GN Name=feoC {ECO:0000255|HAMAP-Rule:MF_01586}; OrderedLocusNames=Ecok1_33805;
GN ORFNames=APECO1_3055.1;
OS Escherichia coli O1:K1 / APEC.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=405955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17293413; DOI=10.1128/jb.01726-06;
RA Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J.,
RA Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K.;
RT "The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7
RT shares strong similarities with human extraintestinal pathogenic E. coli
RT genomes.";
RL J. Bacteriol. 189:3228-3236(2007).
CC -!- FUNCTION: May function as a transcriptional regulator that controls
CC feoABC expression. {ECO:0000255|HAMAP-Rule:MF_01586}.
CC -!- SIMILARITY: Belongs to the FeoC family. {ECO:0000255|HAMAP-
CC Rule:MF_01586}.
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DR EMBL; CP000468; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; WP_000157585.1; NC_008563.1.
DR AlphaFoldDB; P0C602; -.
DR SMR; P0C602; -.
DR Proteomes; UP000008216; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.10; -; 1.
DR HAMAP; MF_01586; FeoC; 1.
DR InterPro; IPR023732; FeoC.
DR InterPro; IPR015102; Tscrpt_reg_HTH_FeoC.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF09012; FeoC; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
PE 3: Inferred from homology;
KW DNA-binding; Iron; Iron-sulfur; Metal-binding; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..78
FT /note="Probable [Fe-S]-dependent transcriptional repressor"
FT /id="PRO_0000313058"
FT BINDING 56
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
FT BINDING 61
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
FT BINDING 64
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
FT BINDING 70
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
SQ SEQUENCE 78 AA; 8641 MW; 95AB9E302CA917AB CRC64;
MASLIQVRDL LALRGRMEAA QISQTLNTPQ PMINAMLKQL ESMGKAVRIQ EEPDGCLSGS
CKSCPEGKAC LHEWWALR