ID   FEOC_KLEP3              Reviewed;          79 AA.
AC   B5XTS6;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2008, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Probable [Fe-S]-dependent transcriptional repressor {ECO:0000255|HAMAP-Rule:MF_01586};
GN   Name=feoC {ECO:0000255|HAMAP-Rule:MF_01586}; OrderedLocusNames=KPK_0335;
OS   Klebsiella pneumoniae (strain 342).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=507522;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=342;
RX   PubMed=18654632; DOI=10.1371/journal.pgen.1000141;
RA   Fouts D.E., Tyler H.L., DeBoy R.T., Daugherty S., Ren Q., Badger J.H.,
RA   Durkin A.S., Huot H., Shrivastava S., Kothari S., Dodson R.J., Mohamoud Y.,
RA   Khouri H., Roesch L.F.W., Krogfelt K.A., Struve C., Triplett E.W.,
RA   Methe B.A.;
RT   "Complete genome sequence of the N2-fixing broad host range endophyte
RT   Klebsiella pneumoniae 342 and virulence predictions verified in mice.";
RL   PLoS Genet. 4:E1000141-E1000141(2008).
CC   -!- FUNCTION: May function as a transcriptional regulator that controls
CC       feoABC expression. {ECO:0000255|HAMAP-Rule:MF_01586}.
CC   -!- SIMILARITY: Belongs to the FeoC family. {ECO:0000255|HAMAP-
CC       Rule:MF_01586}.
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DR   EMBL; CP000964; ACI11375.1; -; Genomic_DNA.
DR   PDB; 4AWX; X-ray; 2.30 A; B=1-79.
DR   PDBsum; 4AWX; -.
DR   AlphaFoldDB; B5XTS6; -.
DR   BMRB; B5XTS6; -.
DR   SMR; B5XTS6; -.
DR   TCDB; 9.A.8.1.10; the ferrous iron uptake (feob) family.
DR   EnsemblBacteria; ACI11375; ACI11375; KPK_0335.
DR   KEGG; kpe:KPK_0335; -.
DR   HOGENOM; CLU_189182_0_0_6; -.
DR   OMA; CLSGGCK; -.
DR   OrthoDB; 1848167at2; -.
DR   Proteomes; UP000001734; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_01586; FeoC; 1.
DR   InterPro; IPR023732; FeoC.
DR   InterPro; IPR015102; Tscrpt_reg_HTH_FeoC.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF09012; FeoC; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   1: Evidence at protein level;
KW   3D-structure; DNA-binding; Iron; Iron-sulfur; Metal-binding; Repressor;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..79
FT                   /note="Probable [Fe-S]-dependent transcriptional repressor"
FT                   /id="PRO_1000201328"
FT   BINDING         56
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
FT   BINDING         61
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
FT   BINDING         64
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
FT   BINDING         71
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
FT   HELIX           4..14
FT                   /evidence="ECO:0007829|PDB:4AWX"
FT   HELIX           19..25
FT                   /evidence="ECO:0007829|PDB:4AWX"
FT   HELIX           30..42
FT                   /evidence="ECO:0007829|PDB:4AWX"
FT   STRAND          45..50
FT                   /evidence="ECO:0007829|PDB:4AWX"
FT   STRAND          74..78
FT                   /evidence="ECO:0007829|PDB:4AWX"
SQ   SEQUENCE   79 AA;  8801 MW;  3C0CF7C969E001EF CRC64;
     MASLMEVRDM LALQGRMEAK QLSARLRTPQ PLIDAMLERM EAMGKVVRIS ETSEGCLSGS
     CKSCPEGKAA CQQEWWALR