FEOC_SALTI
ID FEOC_SALTI Reviewed; 78 AA.
AC Q8XG51; Q7ALV3;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Probable [Fe-S]-dependent transcriptional repressor {ECO:0000255|HAMAP-Rule:MF_01586};
GN Name=feoC {ECO:0000255|HAMAP-Rule:MF_01586};
GN OrderedLocusNames=STY4289, t3999;
OS Salmonella typhi.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=90370;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CT18;
RX PubMed=11677608; DOI=10.1038/35101607;
RA Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA Barrell B.G.;
RT "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT serovar Typhi CT18.";
RL Nature 413:848-852(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700931 / Ty2;
RX PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT CT18.";
RL J. Bacteriol. 185:2330-2337(2003).
CC -!- FUNCTION: May function as a transcriptional regulator that controls
CC feoABC expression. {ECO:0000255|HAMAP-Rule:MF_01586}.
CC -!- SIMILARITY: Belongs to the FeoC family. {ECO:0000255|HAMAP-
CC Rule:MF_01586}.
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DR EMBL; AL513382; CAD08107.1; -; Genomic_DNA.
DR EMBL; AE014613; AAO71469.1; -; Genomic_DNA.
DR RefSeq; NP_458397.1; NC_003198.1.
DR RefSeq; WP_000157589.1; NZ_WSUR01000001.1.
DR AlphaFoldDB; Q8XG51; -.
DR SMR; Q8XG51; -.
DR STRING; 220341.16505086; -.
DR EnsemblBacteria; AAO71469; AAO71469; t3999.
DR KEGG; stt:t3999; -.
DR KEGG; sty:STY4289; -.
DR PATRIC; fig|220341.7.peg.4383; -.
DR eggNOG; ENOG50330S2; Bacteria.
DR HOGENOM; CLU_189182_0_0_6; -.
DR OMA; CLSGGCK; -.
DR Proteomes; UP000000541; Chromosome.
DR Proteomes; UP000002670; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.10; -; 1.
DR HAMAP; MF_01586; FeoC; 1.
DR InterPro; IPR023732; FeoC.
DR InterPro; IPR015102; Tscrpt_reg_HTH_FeoC.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF09012; FeoC; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
PE 3: Inferred from homology;
KW DNA-binding; Iron; Iron-sulfur; Metal-binding; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..78
FT /note="Probable [Fe-S]-dependent transcriptional repressor"
FT /id="PRO_0000313065"
FT BINDING 56
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
FT BINDING 61
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
FT BINDING 64
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
FT BINDING 70
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01586"
SQ SEQUENCE 78 AA; 8674 MW; 61A6D9D0A7FA2594 CRC64;
MASLIQVRDL LALRGRMEAT QISHTLHAPQ PMIDAMLNQL EIMGKAVRIP EEPDGCLSGS
CKSCPEGKAC LREWWALR